Interactor 1: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Interactor 2: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, Helicase_C~Helicase_C
Common GO terms GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway
GO:0003677 - DNA binding
GO:0003678 - DNA helicase activity
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
and 78 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 662
Hs

1 662
+ Hs
+ Hs
+ Sc
+ Ce
+ Ce
+ Ce
+ Hs
+ Sc
+ Hs
+ Hs
+ Sc
+ Dm
+ Dm
+ Dm

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Last updated: 11Aug2025