HitPredict

Interactor 1: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Interactor 2: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

The method score is based on:

Property	Details
Experiments	35562734, 36300783, 37776851
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005524 - ATP binding GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm and 8 others more... GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule GO:0016887 - ATP hydrolysis activity GO:0034774 - secretory granule lumen GO:0070062 - extracellular exosome GO:0090263 - positive regulation of canonical Wnt signaling pathway GO:1901224 - positive regulation of non-canonical NF-kappaB signal transduction GO:1904813 - ficolin-1-rich granule lumen
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	662
Hs

1	806

Service provided by Combinatics, Japan

Last updated: 11Aug2025