HitPredict

Interactor 1: PRP46 (O13615)
Pre-mRNA-splicing factor prp5 (Complexed with cdc5 protein 1) (Pre-mRNA-processing protein 5)
Gene: prp5

Interactor 2: YK99 (Q9HE06)
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase C20H4.09 (EC 3.6.4.13) (DEAH-box helicase C20H4.09)
Gene: SPAC20H4.09

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36361590
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0045292 - mRNA cis splicing, via spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 473 Sp			1 647
+	Zm
		18259 A0A1D6J4G2_MAIZE (2-360): 1.41e-85: 275: 15.14		A0A1D6H4I5_MAIZE (18-645): 0: 733: 38.73
+	Sc
		589467 PRP46_YEAST (111-398): 2.9e-59: 203: 22.26		PRP2_YEAST (5-644): 0: 756: 33.78
+	Hs
		1268349 FBW1A_HUMAN (103-399): 2.36e-67: 228: 25.48		PRP16_HUMAN (7-647): 0: 701: 35.44
+	Hs
		195578 FBW1A_HUMAN (103-399): 2.36e-67: 228: 25.48		DHX15_HUMAN (4-645): 0: 699: 37.86
+	Hs
		224824 FBXW7_HUMAN (3-312): 8e-65: 223: 16.51		DHX16_HUMAN (20-647): 0: 693: 38.15
+	Hs
		195393 WDR5_HUMAN (281-472): 2.99e-55: 189: 21.03		DHX15_HUMAN (4-645): 0: 699: 37.86
+	Hs
		1055447 SNR40_HUMAN (281-472): 3.97e-45: 162: 20.41		DHX8_HUMAN (7-645): 0: 723: 39.94
+	Sc
		622354 PRP46_YEAST (111-398): 2.9e-59: 203: 22.26		PRP22_YEAST (4-647): 0: 677: 38.19
+	Hs
		209435 PLRG1_HUMAN (1-232): 2.22e-37: 145: 11.84		DHX8_HUMAN (7-645): 0: 723: 39.94
+	Sc
		859466 PRP46_YEAST (111-398): 2.9e-59: 203: 22.26		PRP43_YEAST (2-645): 0: 662: 38.73
+	Hs
		1268324 SNR40_HUMAN (281-472): 3.97e-45: 162: 20.41		PRP16_HUMAN (7-647): 0: 701: 35.44
+	Hs
		224827 SNR40_HUMAN (281-472): 3.97e-45: 162: 20.41		DHX16_HUMAN (20-647): 0: 693: 38.15
+	Sc
		554258 PRP46_YEAST (111-398): 2.9e-59: 203: 22.26		PRP16_YEAST (22-643): 0: 615: 37.50
+	Hs
		1055513 PRP19_HUMAN (318-473): 2.58e-19: 92.2: 14.72		DHX8_HUMAN (7-645): 0: 723: 39.94
+	Hs
		1288306 SNR40_HUMAN (281-472): 3.97e-45: 162: 20.41		DHX35_HUMAN (18-644): 0: 650: 40.31
+	Hs
		994406 FBW1A_HUMAN (103-399): 2.36e-67: 228: 25.48		DHX9_HUMAN (1-646): 0: 577: 25.45
+	Hs
		994278 FBXW7_HUMAN (3-312): 8e-65: 223: 16.51		DHX9_HUMAN (1-646): 0: 577: 25.45
+	Hs
		209480 PLRG1_HUMAN (1-232): 2.22e-37: 145: 11.84		DHX35_HUMAN (18-644): 0: 650: 40.31
+	Hs
		903167 WDR5_HUMAN (281-472): 2.99e-55: 189: 21.03		DHX9_HUMAN (1-646): 0: 577: 25.45
+	Sc
		630874 NLE1_YEAST (15-151): 1.77e-20: 96: 7.69		PRP43_YEAST (2-645): 0: 662: 38.73