Protein: MFAP4
Microfibril-associated glycoprotein 4

Gene: MFAP4
Organism: Homo sapiens
Interactions: 159
UniProt ID: P55083

Gene Ontology (top 5):
GO:0001527 - microfibril
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0007155 - cell adhesion
GO:0009650 - UV protection

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

282831

CRLF1
Cytokine receptor-like factor 1

1

2

High-throughput

0.691

High

935775

PTPRU
Receptor-type tyrosine-protein phosphatase U

1

4

High-throughput

0.691

High

935790

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

1

3

High-throughput

0.618

High

935716

TLE2
Transducin-like enhancer protein 2

2

7

High-throughput

0.601

High

935756

LDB1
LIM domain-binding protein 1

2

0

High-throughput

0.576

High

935715

TLE1
Transducin-like enhancer protein 1

2

7

High-throughput

0.549

High

935717

TLE3
Transducin-like enhancer protein 3

2

7

High-throughput

0.549

High

935718

TLE4
Transducin-like enhancer protein 4

2

7

High-throughput

0.549

High

935720

TLE5
TLE family member 5

2

6

High-throughput

0.549

High

935774

TBCD5
TBC1 domain family member 5

2

1

High-throughput

0.549

High

935792

SSBP4
Single-stranded DNA-binding protein 4

2

3

High-throughput

0.549

High

935794

SSBP3
Single-stranded DNA-binding protein 3

2

3

High-throughput

0.549

High

133178

QSOX1
Sulfhydryl oxidase 1

1

2

High-throughput

0.536

High

183236

LAMA5
Laminin subunit alpha-5

1

8

High-throughput

0.536

High

320867

LRIG2
Leucine-rich repeats and immunoglobulin-like domains protein 2

1

2

High-throughput

0.536

High

336190

TNF6B
Tumor necrosis factor receptor superfamily member 6B

1

1

High-throughput

0.536

High

350696

NOE2
Noelin-2

1

2

High-throughput

0.536

High

366480

UROK
Urokinase-type plasminogen activator

1

7

High-throughput

0.536

High

452213

PDIA1
Protein disulfide-isomerase

1

1

High-throughput

0.536

High

464431

TSP1
Thrombospondin-1

1

4

High-throughput

0.536

High

562709

BMP1
Bone morphogenetic protein 1

1

10

High-throughput

0.536

High

586369

ARSB
Arylsulfatase B

1

5

High-throughput

0.536

High

650104

FGFR3
Fibroblast growth factor receptor 3

1

6

High-throughput

0.536

High

704433

GRAN
Grancalcin

1

2

High-throughput

0.536

High

709055

PCSK6
Proprotein convertase subtilisin/kexin type 6

1

7

High-throughput

0.536

High

756539

GALNS
N-acetylgalactosamine-6-sulfatase

1

5

High-throughput

0.536

High

760791

BMP8B
Bone morphogenetic protein 8B

1

3

High-throughput

0.536

High

810594

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

2

High-throughput

0.536

High

902990

MMP15
Matrix metalloproteinase-15

1

2

High-throughput

0.536

High

935710

LAMB2
Laminin subunit beta-2

1

7

High-throughput

0.536

High

935721

LOXL1
Lysyl oxidase homolog 1

1

1

High-throughput

0.536

High

935726

SEM3B
Semaphorin-3B

1

2

High-throughput

0.536

High

935727

DNJC3
DnaJ homolog subfamily C member 3

1

2

High-throughput

0.536

High

935730

LAMB3
Laminin subunit beta-3

1

6

High-throughput

0.536

High

935744

GT253
Inactive glycosyltransferase 25 family member 3

1

2

High-throughput

0.536

High

935746

METRL
Meteorin-like protein

1

1

High-throughput

0.536

High

935747

SCAR3
Scavenger receptor class A member 3

1

1

High-throughput

0.536

High

935750

CSPG4
Chondroitin sulfate proteoglycan 4

1

2

High-throughput

0.536

High

935752

ARSK
Arylsulfatase K

1

5

High-throughput

0.536

High

935753

THSD4
Thrombospondin type-1 domain-containing protein 4

1

1

High-throughput

0.536

High

935760

CILP2
Cartilage intermediate layer protein 2

1

2

High-throughput

0.536

High

935772

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

1

High-throughput

0.536

High

935781

I17RA
Interleukin-17 receptor A

1

1

High-throughput

0.536

High

935782

NAR5
Ecto-ADP-ribosyltransferase 5

1

1

High-throughput

0.536

High

935788

SEM3C
Semaphorin-3C

1

2

High-throughput

0.536

High

935799

ADA19
Disintegrin and metalloproteinase domain-containing protein 19

1

1

High-throughput

0.536

High

935800

CHRD
Chordin

1

15

High-throughput

0.536

High

935814

METRN
Meteorin

1

1

High-throughput

0.536

High

935815

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

3

High-throughput

0.536

High

935821

LOXL2
Lysyl oxidase homolog 2

1

3

High-throughput

0.536

High

935824

TLL2
Tolloid-like protein 2

1

10

High-throughput

0.536

High

327104

NXPH4
Neurexophilin-4

1

0

High-throughput

0.513

High

467823

BGLR
Beta-glucuronidase

1

0

High-throughput

0.513

High

571230

PERF
Perforin-1

1

0

High-throughput

0.513

High

660252

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.513

High

720452

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.513

High

935724

HYAL2
Hyaluronidase-2

1

0

High-throughput

0.513

High

935780

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.513

High

935793

CHID1
Chitinase domain-containing protein 1

1

0

High-throughput

0.513

High

935795

TX101
Testis-expressed protein 101

1

0

High-throughput

0.513

High

935816

HPSE
Heparanase

1

0

High-throughput

0.513

High

935817

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.513

High

935823

AGRG1
Adhesion G-protein coupled receptor G1

1

0

High-throughput

0.513

High

772275

FBN1
Fibrillin-1 [Cleaved into: Asprosin]

1

5

Small-scale

0.494

High

160815

TOR1B
Torsin-1B

1

3

High-throughput

0.489

High

253009

LMX1B
LIM homeobox transcription factor 1-beta

1

1

High-throughput

0.489

High

269659

PLXA2
Plexin-A2

1

3

High-throughput

0.489

High

338729

NPTXR
Neuronal pentraxin receptor

1

5

High-throughput

0.489

High

885461

MA2A2
Alpha-mannosidase 2x

1

2

High-throughput

0.489

High

907208

SPHM
N-sulphoglucosamine sulphohydrolase

1

5

High-throughput

0.489

High

907891

PLXA3
Plexin-A3

1

3

High-throughput

0.489

High

935713

SSBP2
Single-stranded DNA-binding protein 2

1

4

High-throughput

0.489

High

935719

CSTF1
Cleavage stimulation factor subunit 1

1

1

High-throughput

0.489

High

935733

MBTP1
Membrane-bound transcription factor site-1 protease

1

3

High-throughput

0.489

High

935740

TBB8
Tubulin beta-8 chain

1

2

High-throughput

0.489

High

935741

OFUT4
GDP-fucose protein O-fucosyltransferase 4

1

1

High-throughput

0.489

High

935745

TASO2
Protein TASOR 2

1

2

High-throughput

0.489

High

935751

PLGT2
Protein O-glucosyltransferase 2

1

3

High-throughput

0.489

High

935755

PLGT3
Protein O-glucosyltransferase 3

1

3

High-throughput

0.489

High

935757

OAF
Out at first protein homolog

1

1

High-throughput

0.489

High

935761

P3H3
Prolyl 3-hydroxylase 3

1

2

High-throughput

0.489

High

935764

PGLT1
Protein O-glucosyltransferase 1

1

3

High-throughput

0.489

High

935766

TTC13
Tetratricopeptide repeat protein 13

1

4

High-throughput

0.489

High

935768

CHSTE
Carbohydrate sulfotransferase 14

1

1

High-throughput

0.489

High

935771

GPX8
Probable glutathione peroxidase 8

1

1

High-throughput

0.489

High

935776

SC65
Endoplasmic reticulum protein SC65

1

2

High-throughput

0.489

High

935777

ISL2
Insulin gene enhancer protein ISL-2

1

1

High-throughput

0.489

High

935787

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

3

High-throughput

0.489

High

935796

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

1

High-throughput

0.489

High

935797

FUT8
Alpha-(1,6)-fucosyltransferase

1

1

High-throughput

0.489

High

935798

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

4

High-throughput

0.489

High

935801

SEM6B
Semaphorin-6B

1

2

High-throughput

0.489

High

935802

CHSTC
Carbohydrate sulfotransferase 12

1

1

High-throughput

0.489

High

935807

CA2D2
Voltage-dependent calcium channel subunit alpha-2/delta-2

1

1

High-throughput

0.489

High

935810

CHPF2
Chondroitin sulfate glucuronyltransferase

1

1

High-throughput

0.489

High

935813

PLXA1
Plexin-A1

1

4

High-throughput

0.489

High

935819

MA2B2
Epididymis-specific alpha-mannosidase

1

2

High-throughput

0.489

High

452086

PROS
Vitamin K-dependent protein S

1

10

High-throughput

0.445

High

935731

GAS6
Growth arrest-specific protein 6

1

8

High-throughput

0.445

High

935784

CNT3B
Contactin-associated protein-like 3B

1

2

High-throughput

0.445

High

935803

OLFL3
Olfactomedin-like protein 3

1

2

High-throughput

0.445

High

935804

LTBP3
Latent-transforming growth factor beta-binding protein 3

1

6

High-throughput

0.445

High

935818

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.445

High

935822

RN115
E3 ubiquitin-protein ligase RNF115

1

1

Small-scale

0.439

High

170030

AURKA
Aurora kinase A

1

4

High-throughput

0.437

High

413483

P53
Cellular tumor antigen p53

1

1

High-throughput

0.437

High

872115

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.437

High

935712

GRB2
Growth factor receptor-bound protein 2

1

1

High-throughput

0.437

High

520795

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.426

High

935786

NEUR1
Sialidase-1

1

0

High-throughput

0.426

High

534834

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.407

High

551978

ADT1
ADP/ATP translocase 1

1

4

High-throughput

0.407

High

935711

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

1

1

High-throughput

0.407

High

935729

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

5

High-throughput

0.407

High

935754

TBA1A
Tubulin alpha-1A chain

1

2

High-throughput

0.407

High

935789

TBA1C
Tubulin alpha-1C chain

1

2

High-throughput

0.407

High

935812

CEIP2
Cell surface hyaluronidase CEMIP2

1

1

High-throughput

0.407

High

935736

OCLN
Occludin

2

0

High-throughput

0.328

High

935728

KCAB2
Voltage-gated potassium channel subunit beta-2

2

0

High-throughput

0.313

High

231690

PEX1
Peroxisomal ATPase PEX1

1

0

High-throughput

0.279

Low

771656

IDUA
Alpha-L-iduronidase

1

0

High-throughput

0.279

Low

932356

ANAG
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.279

Low

935714

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

935722

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

0

High-throughput

0.279

Low

935725

CSTF3
Cleavage stimulation factor subunit 3

1

0

High-throughput

0.279

Low

935732

MELK
Maternal embryonic leucine zipper kinase

1

0

High-throughput

0.279

Low

935735

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.279

Low

935737

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

0

High-throughput

0.279

Low

935738

T132A
Transmembrane protein 132A

1

0

High-throughput

0.279

Low

935739

CL16A
Protein CLEC16A

1

0

High-throughput

0.279

Low

935742

TIGD5
Tigger transposable element-derived protein 5

1

0

High-throughput

0.279

Low

935743

FKB15
FK506-binding protein 15

1

0

High-throughput

0.279

Low

935748

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

0

High-throughput

0.279

Low

935758

ZN589
Zinc finger protein 589

1

0

High-throughput

0.279

Low

935759

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

0

High-throughput

0.279

Low

935762

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.279

Low

935763

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.279

Low

935765

RDH13
Retinol dehydrogenase 13

1

0

High-throughput

0.279

Low

935767

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

High-throughput

0.279

Low

935769

PPHLN
Periphilin-1

1

0

High-throughput

0.279

Low

935770

RS4Y2
Small ribosomal subunit protein eS4, Y isoform 2

1

0

High-throughput

0.279

Low

935773

TM131
Transmembrane protein 131

1

0

High-throughput

0.279

Low

935778

TTC17
Tetratricopeptide repeat protein 17

1

0

High-throughput

0.279

Low

935779

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.279

Low

935783

H6ST2
Heparan-sulfate 6-O-sulfotransferase 2

1

0

High-throughput

0.279

Low

935785

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.279

Low

935791

LMF2
Lipase maturation factor 2

1

0

High-throughput

0.279

Low

935805

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.279

Low

935808

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

0

High-throughput

0.279

Low

935809

SELN
Selenoprotein N

1

0

High-throughput

0.279

Low

935811

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.279

Low

259687

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

935820

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

Small-scale

0.249

Low

755471

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.232

Low

935723

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.232

Low

935734

ABRX2
BRISC complex subunit Abraxas 2

1

0

High-throughput

0.232

Low

935749

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

0

High-throughput

0.232

Low

935806

BABA2
BRISC and BRCA1-A complex member 2

1

0

High-throughput

0.232

Low

935825

SQOR
Sulfide:quinone oxidoreductase, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025