HitPredict

Interactor 1: CSE1 (O13671)
Importin-alpha re-exporter (Cellular apoptosis susceptibility protein homolog)
Gene: kap109

Interactor 2: SPI1 (P28748)
GTP-binding nuclear protein spi1
Gene: SPI1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	26771498
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CAS_CSE1~Ras, Cse1~Ras, IBN_N~Ras
Common GO terms	GO:0005525 - GTP binding GO:0005829 - cytosol GO:0006606 - protein import into nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 967 Sp			1 216
+	Hs
		874484 XPO2_HUMAN (1-963): 0: 687: 38.21		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Hs
		312234 IPO7_HUMAN (2-964): 7.29e-178: 546: 16.86		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Sc
		698750 CSE1_YEAST (1-961): 7.8e-176: 538: 40.06		GSP1_YEAST (1-216): 6.2e-87: 257: 87.22
+	Hs
		178143 IPO8_HUMAN (1-962): 3.24e-169: 523: 17.28		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Sc
		698999 CSE1_YEAST (1-961): 7.8e-176: 538: 40.06		GSP2_YEAST (1-216): 5.96e-81: 242: 86.82
+	Hs
		919198 TNPO1_HUMAN (9-963): 9.93e-148: 463: 11.37		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Dm
		1373317 Q9VRV8_DROME (1-962): 2.97e-144: 453: 12.34		RANL_DROME (3-216): 7.85e-90: 265: 59.26
+	At
		1210454 IMB1_ARATH (3-914): 2.19e-132: 422: 11.75		RAN3_ARATH (2-213): 9.26e-99: 287: 75.94
+	Hs
		155560 TNPO2_HUMAN (9-963): 5.04e-141: 445: 11.92		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	At
		784992 IMB1_ARATH (3-914): 2.19e-132: 422: 11.75		RAN1_ARATH (2-213): 1.18e-95: 279: 75.00
+	At
		784999 IMB1_ARATH (3-914): 2.19e-132: 422: 11.75		RAN2_ARATH (2-213): 1.08e-89: 264: 75.47
+	Sc
		698917 KA120_YEAST (3-961): 9.14e-131: 421: 14.94		GSP1_YEAST (1-216): 6.2e-87: 257: 87.22
+	Sc
		699016 KA120_YEAST (3-961): 9.14e-131: 421: 14.94		GSP2_YEAST (1-216): 5.96e-81: 242: 86.82
+	At
		784988 TNPO1_ARATH (1-963): 2.3e-116: 380: 12.50		RAN1_ARATH (2-213): 1.18e-95: 279: 75.00
+	Sc
		698861 NMD5_YEAST (3-840): 5.84e-123: 401: 15.53		GSP1_YEAST (1-216): 6.2e-87: 257: 87.22
+	Hs
		919299 IPO11_HUMAN (1-963): 5.33e-120: 391: 16.39		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Hs
		919077 IMB1_HUMAN (3-816): 4.06e-116: 378: 10.92		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Hs
		919222 IPO9_HUMAN (1-850): 1.37e-114: 378: 13.31		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Sc
		698930 SXM1_YEAST (2-961): 4.23e-93: 318: 17.15		GSP1_YEAST (1-216): 6.2e-87: 257: 87.22