HitPredict

Interactor 1: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 456
+	Hs
		1429021 WWTR1_HUMAN (1-400): 5.18e-126: 371: 100.00		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		862567 YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		862565 YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		132388 WWP2_HUMAN (3-220): 6.69e-59: 207: 19.46		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		1230936 WWC2_HUMAN (121-264): 2.85e-43: 163: 15.97		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		132386 WWP2_HUMAN (3-220): 6.69e-59: 207: 19.46		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		861845 NEDD4_HUMAN (109-352): 7.43e-23: 103: 11.00		RUVB1_HUMAN (1-456): 0: 704: 100.00