Protein: WWC2
Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2)

Gene: WWC2
Organism: Homo sapiens
Interactions: 35
UniProt ID: Q6AWC2

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006355 - regulation of DNA-templated transcription
GO:0008285 - negative regulation of cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1230927

KIBRA
Protein KIBRA

1

16

Small-scale

0.713

High

1230934

WWC3
Protein WWC3

1

16

Small-scale

0.713

High

729939

1433B
14-3-3 protein beta/alpha

5

20

High-throughput

0.709

High

966464

1433G
14-3-3 protein gamma

4

20

High-throughput

0.691

High

1049417

1433F
14-3-3 protein eta

4

20

High-throughput

0.691

High

991574

DYL1
Dynein light chain 1, cytoplasmic

3

4

High-throughput

0.662

High

1230928

RHPN1
Rhophilin-1

3

20

High-throughput

0.662

High

990348

1433Z
14-3-3 protein zeta/delta

3

20

High-throughput

0.656

High

1230930

DYL2
Dynein light chain 2, cytoplasmic

3

4

High-throughput

0.650

High

691122

1433T
14-3-3 protein theta

3

20

High-throughput

0.641

High

1151996

PTN14
Tyrosine-protein phosphatase non-receptor type 14

3

20

Small-scale

0.640

High

1230924

WWC2
Protein WWC2

1

16

Small-scale

0.621

High

862216

YAP1
Transcriptional coactivator YAP1

1

19

Small-scale

0.618

High

971640

1433E
14-3-3 protein epsilon

2

11

High-throughput

0.611

High

1163725

PTN21
Tyrosine-protein phosphatase non-receptor type 21

2

20

High-throughput

0.611

High

180996

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

3

14

High-throughput

0.609

High

384445

CRYAA
Alpha-crystallin A chain

1

8

High-throughput

0.501

High

1230929

REPS1
RalBP1-associated Eps domain-containing protein 1

1

6

High-throughput

0.481

High

172940

XPO1
Exportin-1

1

17

High-throughput

0.479

High

349125

LATS1
Serine/threonine-protein kinase LATS1

1

20

Small-scale

0.479

High

363416

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.479

High

452295

PDIA1
Protein disulfide-isomerase

1

10

High-throughput

0.479

High

603295

KPCA
Protein kinase C alpha type

1

20

Small-scale

0.479

High

730669

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

920037

PLK1
Serine/threonine-protein kinase PLK1

1

11

High-throughput

0.479

High

1230931

RHG07
Rho GTPase-activating protein 7

1

12

Small-scale

0.479

High

1230933

LATS2
Serine/threonine-protein kinase LATS2

1

20

Small-scale

0.479

High

1230935

ODF2L
Protein BCAP

1

13

High-throughput

0.479

High

1230936

RUVB1
RuvB-like 1

1

3

High-throughput

0.479

High

1186170

INAVA
Innate immunity activator protein

1

1

High-throughput

0.445

High

1230926

ARMC8
Armadillo repeat-containing protein 8

1

5

High-throughput

0.445

High

1155151

EREP1
Endosomal transmembrane epsin interactor 1

1

14

Small-scale

0.417

High

1230925

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

8

High-throughput

0.407

High

1230932

TSYL1
Testis-specific Y-encoded-like protein 1

1

4

High-throughput

0.407

High


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Last updated: 11Aug2025