HitPredict

Interactor 1: RU17 (O13829)
U1 small nuclear ribonucleoprotein 70 kDa homolog (U1 70K) (U1 snRNP 70 kDa homolog) (U1-70K) (U1 small nuclear ribonucleoprotein usp101) (U1 snRNP protein usp101)
Gene: usp101

Interactor 2: RU1A (O74968)
U1 small nuclear ribonucleoprotein usp102 (U1 snRNP protein usp102)
Gene: usp102

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	17264129
Identification Methods	biochemical
Interaction Type	association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~U1snRNP70_N
Common GO terms	GO:0000395 - mRNA 5'-splice site recognition GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005685 - U1 snRNP GO:0030619 - U1 snRNA binding and 1 others more... GO:0071004 - U2-type prespliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 261 Sp			1 249
+	Dm
		565303 RU17_DROME (1-186): 1.54e-48: 168: 40.96		SNRPA_DROME (21-247): 1.46e-72: 222: 35.09
+	Hs
		442125 RU17_HUMAN (1-184): 4.6e-49: 169: 44.39		PABP4_HUMAN (1-199): 1.05e-23: 101: 14.29
+	Hs
		441852 RU17_HUMAN (1-184): 4.6e-49: 169: 44.39		PABP1_HUMAN (1-195): 1.98e-23: 100: 15.00
+	Hs
		442076 RU17_HUMAN (1-184): 4.6e-49: 169: 44.39		TIAR_HUMAN (3-153): 2.54e-17: 82.1: 15.48
+	Hs
		442112 RU17_HUMAN (1-184): 4.6e-49: 169: 44.39		ELAV2_HUMAN (27-108): 4.36e-17: 81.3: 22.35
+	Hs
		441896 RU17_HUMAN (1-184): 4.6e-49: 169: 44.39		TIA1_HUMAN (19-172): 6.68e-14: 72.1: 11.69
+	Hs
		441837 RU17_HUMAN (1-184): 4.6e-49: 169: 44.39		SNRPA_HUMAN (168-249): 2.25e-13: 69.7: 21.59
+	Hs
		441891 RU17_HUMAN (1-184): 4.6e-49: 169: 44.39		PTBP1_HUMAN (24-249): 7.3e-13: 69.4: 18.18
+	Mm
		857334 RU17_MOUSE (1-184): 4.4e-49: 169: 44.39		TIA1_MOUSE (168-249): 6.02e-13: 69.3: 23.53
+	Hs
		235672 RU17_HUMAN (1-184): 4.6e-49: 169: 44.39		HNRPQ_HUMAN (10-135): 2.08e-11: 65.1: 17.83
+	Hs
		441212 RU17_HUMAN (1-184): 4.6e-49: 169: 44.39		RU2B_HUMAN (171-249): 6.09e-12: 65.1: 20.00
+	Hs
		1031490 PUF60_HUMAN (7-191): 1.75e-32: 126: 18.82		PABP4_HUMAN (1-199): 1.05e-23: 101: 14.29
+	Hs
		516730 PUF60_HUMAN (7-191): 1.75e-32: 126: 18.82		PABP1_HUMAN (1-195): 1.98e-23: 100: 15.00
+	Hs
		321091 U1SBP_HUMAN (53-260): 1.46e-36: 131: 32.21		PTBP3_HUMAN (15-246): 3.34e-18: 85.2: 20.51
+	Hs
		321239 PUF60_HUMAN (7-191): 1.75e-32: 126: 18.82		PTBP3_HUMAN (15-246): 3.34e-18: 85.2: 20.51
+	Sc
		696657 RU17_YEAST (3-261): 1.8e-37: 135: 34.96		RU1A_YEAST (110-246): 1.43e-11: 64.7: 27.54
+	Hs
		446829 PUF60_HUMAN (7-191): 1.75e-32: 126: 18.82		SNRPA_HUMAN (168-249): 2.25e-13: 69.7: 21.59
+	Hs
		1355614 PUF60_HUMAN (7-191): 1.75e-32: 126: 18.82		PTBP2_HUMAN (17-246): 1.19e-12: 69: 19.15
+	Hs
		446627 CIRBP_HUMAN (98-253): 3.33e-35: 125: 27.61		SNRPA_HUMAN (168-249): 2.25e-13: 69.7: 21.59
+	Hs
		236122 PUF60_HUMAN (7-191): 1.75e-32: 126: 18.82		HNRPQ_HUMAN (10-135): 2.08e-11: 65.1: 17.83