Interactor 1: PKHF2 (Q9H8W4)
Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2) (Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains) (EAPF) (PH and FYVE domain-containing protein 2) (Phafin-2) (Phafin2) (Zinc finger FYVE domain-containing protein 18)
Gene: PLEKHF2
Interactor 2: DP13A (Q9UKG1)
DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)
Gene: APPL1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.723 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19060904 |
| Identification Methods | two hybrid, two hybrid array, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BAR_3~PH, PH~PH |
| Common GO terms | GO:0005769 - early endosome GO:0031901 - early endosome membrane GO:0035091 - phosphatidylinositol binding |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
