Protein: DP13A
DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)

Gene: DP13A, APPL1
Organism: Homo sapiens
Interactions: 180
UniProt ID: Q9UKG1

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0001786 - phosphatidylserine binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005768 - endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1337806

DP13B
DCC-interacting protein 13-beta

12

16

Small-scale

0.983

High

1461081

DP13A
DCC-interacting protein 13-alpha

8

14

Small-scale

0.971

High

631550

RAB5A
Ras-related protein Rab-5A

8

13

Small-scale

0.968

High

728473

AKT1
RAC-alpha serine/threonine-protein kinase

5

7

Small-scale

0.904

High

728629

AKT2
RAC-beta serine/threonine-protein kinase

3

8

Small-scale

0.874

High

1353633

GIPC2
PDZ domain-containing protein GIPC2

3

3

High-throughput

0.861

High

1159044

RBBP7
Histone-binding protein RBBP7

2

2

Small-scale

0.799

High

167664

GIPC1
PDZ domain-containing protein GIPC1

2

3

High-throughput

0.789

High

364007

EGFR
Epidermal growth factor receptor

2

16

High-throughput

0.768

High

249794

DOK2
Docking protein 2

2

5

High-throughput

0.767

High

1272302

DOK3
Docking protein 3

2

4

High-throughput

0.767

High

1449420

BRWD1
Bromodomain and WD repeat-containing protein 1

2

1

High-throughput

0.767

High

412783

NTRK1
High affinity nerve growth factor receptor

2

15

High-throughput

0.754

High

710557

EPHA2
Ephrin type-A receptor 2

2

7

High-throughput

0.754

High

1347269

REBL1
GTPase RhebL1

1

5

High-throughput

0.740

High

1066542

RBBP4
Histone-binding protein RBBP4

2

2

Small-scale

0.737

High

1166388

DOK7
Protein Dok-7

2

0

High-throughput

0.728

High

1436621

PKHF2
Pleckstrin homology domain-containing family F member 2

1

1

High-throughput

0.723

High

896926

DYN2
Dynamin-2

1

2

High-throughput

0.698

High

376077

RASK
GTPase KRas

1

8

High-throughput

0.691

High

783175

ARL3
ADP-ribosylation factor-like protein 3

1

12

High-throughput

0.691

High

942950

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

13

High-throughput

0.691

High

1450635

ARL8B
ADP-ribosylation factor-like protein 8B

1

9

High-throughput

0.691

High

1454169

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

2

High-throughput

0.691

High

787464

TGFR1
TGF-beta receptor type-1

1

0

Small-scale

0.687

High

1382485

PAQR1
Adiponectin receptor protein 1

3

2

Small-scale

0.675

High

848743

MAGA9
Melanoma-associated antigen 9

3

2

High-throughput

0.675

High

1368195

HDAC2
Histone deacetylase 2

3

4

Small-scale

0.675

High

334474

SYFM
Phenylalanine--tRNA ligase, mitochondrial

4

0

High-throughput

0.668

High

1053282

Q05BL1
TP53BP2 protein

1

3

High-throughput

0.665

High

1367893

ARC1A
Actin-related protein 2/3 complex subunit 1A

1

0

High-throughput

0.656

High

1098859

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

4

Small-scale

0.647

High

1461082

RAB21
Ras-related protein Rab-21

1

16

Small-scale

0.647

High

1461083

RB22A
Ras-related protein Rab-22A

1

14

Small-scale

0.647

High

1420993

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

3

0

High-throughput

0.646

High

651458

CBL
E3 ubiquitin-protein ligase CBL

3

6

High-throughput

0.646

High

699887

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

3

5

Small-scale

0.646

High

188385

HDAC3
Histone deacetylase 3

2

3

Small-scale

0.646

High

1461089

RTCB
RNA-splicing ligase RtcB homolog

2

1

High-throughput

0.634

High

663534

FSHR
Follicle-stimulating hormone receptor

2

2

Small-scale

0.633

High

1340751

TPC2
Two pore channel protein 2

2

2

High-throughput

0.628

High

1115627

ASPP2
Apoptosis-stimulating of p53 protein 2

1

3

High-throughput

0.621

High

317031

MTA2
Metastasis-associated protein MTA2

2

1

Small-scale

0.619

High

1110169

HDAC1
Histone deacetylase 1

2

4

Small-scale

0.619

High

465689

IGF1R
Insulin-like growth factor 1 receptor

1

15

Small-scale

0.618

High

541751

FGFR1
Fibroblast growth factor receptor 1

1

16

High-throughput

0.618

High

593531

PGFRA
Platelet-derived growth factor receptor alpha

1

6

High-throughput

0.618

High

648727

FGFR4
Fibroblast growth factor receptor 4

1

17

High-throughput

0.618

High

931912

EPHA5
Ephrin type-A receptor 5

1

10

High-throughput

0.618

High

978392

RHOB
Rho-related GTP-binding protein RhoB

1

16

High-throughput

0.618

High

1006118

DLG4
Disks large homolog 4

1

7

Small-scale

0.618

High

1051335

KPCZ
Protein kinase C zeta type

1

8

Small-scale

0.618

High

1147462

EPHA7
Ephrin type-A receptor 7

1

9

High-throughput

0.618

High

1157106

NTRK3
NT-3 growth factor receptor

1

14

High-throughput

0.618

High

1159553

NTRK2
BDNF/NT-3 growth factors receptor

1

16

High-throughput

0.618

High

1434195

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.618

High

1461087

AKT3
RAC-gamma serine/threonine-protein kinase

1

7

Small-scale

0.618

High

329119

KLHL2
Kelch-like protein 2

2

4

High-throughput

0.611

High

414813

P53
Cellular tumor antigen p53

3

0

High-throughput

0.609

High

1090973

TRAF2
TNF receptor-associated factor 2

2

2

High-throughput

0.608

High

156094

SOCS6
Suppressor of cytokine signaling 6

2

18

High-throughput

0.594

High

832338

ID1
DNA-binding protein inhibitor ID-1

2

1

High-throughput

0.594

High

1097959

CBLB
E3 ubiquitin-protein ligase CBL-B

2

6

High-throughput

0.594

High

1185839

ZN829
Zinc finger protein 829

2

1

High-throughput

0.594

High

1350843

MAGC3
Melanoma-associated antigen C3

2

2

High-throughput

0.594

High

1445800

SH22A
SH2 domain-containing protein 2A

2

20

High-throughput

0.594

High

1447985

BATF3
Basic leucine zipper transcriptional factor ATF-like 3

2

1

High-throughput

0.594

High

1460382

KLF15
Krueppel-like factor 15

2

2

High-throughput

0.594

High

1398936

ZN830
Zinc finger protein 830

2

0

High-throughput

0.585

High

1034084

OCRL
Inositol polyphosphate 5-phosphatase OCRL

2

0

Small-scale

0.585

High

243254

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.584

High

1400238

PNMA5
Paraneoplastic antigen-like protein 5

2

0

High-throughput

0.580

High

1414928

MTND
Acireductone dioxygenase

2

0

High-throughput

0.580

High

136445

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

2

19

High-throughput

0.576

High

1417670

SCAPE
S phase cyclin A-associated protein in the endoplasmic reticulum

2

3

High-throughput

0.576

High

922340

LIMK2
LIM domain kinase 2

1

6

High-throughput

0.575

High

893756

MEOX1
Homeobox protein MOX-1

1

2

High-throughput

0.573

High

297379

DYSF
Dysferlin

1

3

High-throughput

0.568

High

1461086

RUVB2
RuvB-like 2

1

1

Small-scale

0.561

High

846000

DCC
Netrin receptor DCC

1

3

Small-scale

0.552

High

1289841

PAQR2
Adiponectin receptor protein 2

1

2

Small-scale

0.552

High

138535

BIN1
Myc box-dependent-interacting protein 1

1

3

High-throughput

0.541

High

174143

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.541

High

288039

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

1

High-throughput

0.541

High

415926

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.541

High

1040400

DYST
Dystonin

1

1

High-throughput

0.541

High

1146289

ANKR1
Ankyrin repeat domain-containing protein 1

1

2

High-throughput

0.541

High

1322324

SPART
Spartin

1

2

High-throughput

0.541

High

1360694

SYNE2
Nesprin-2

1

2

High-throughput

0.541

High

1361846

RSPH1
Radial spoke head 1 homolog

1

2

High-throughput

0.541

High

1362037

CTTB2
Cortactin-binding protein 2

1

4

High-throughput

0.541

High

1452542

DACT1
Dapper homolog 1

1

2

High-throughput

0.541

High

1461091

DTNA
Dystrobrevin alpha

1

1

High-throughput

0.541

High

691526

1433T
14-3-3 protein theta

1

16

High-throughput

0.536

High

730342

1433B
14-3-3 protein beta/alpha

1

16

High-throughput

0.536

High

967003

1433G
14-3-3 protein gamma

1

16

High-throughput

0.536

High

972114

1433E
14-3-3 protein epsilon

1

3

High-throughput

0.536

High

990852

1433Z
14-3-3 protein zeta/delta

1

16

High-throughput

0.536

High

1049895

1433F
14-3-3 protein eta

1

16

High-throughput

0.536

High

1436410

PAAT
ATPase PAAT

1

1

High-throughput

0.536

High

1461085

HDAC5
Histone deacetylase 5

1

5

High-throughput

0.536

High

1461088

RP3A
Rabphilin-3A

1

2

High-throughput

0.536

High

106825

APRIO
Alternative prion protein

2

2

High-throughput

0.533

High

535956

MYH3
Myosin-3

1

0

High-throughput

0.518

High

772636

GDE
Glycogen debranching enzyme

1

0

High-throughput

0.518

High

773798

ACTN2
Alpha-actinin-2

1

0

High-throughput

0.518

High

906368

GPC3
Glypican-3

1

0

High-throughput

0.518

High

1316826

CKLF4
CKLF-like MARVEL transmembrane domain-containing protein 4

1

0

High-throughput

0.518

High

1409539

DPYL5
Dihydropyrimidinase-related protein 5

1

0

High-throughput

0.518

High

1420874

CIPC
CLOCK-interacting pacemaker

1

0

High-throughput

0.518

High

179413

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.513

High

213705

AQP9
Aquaporin-9

1

0

High-throughput

0.513

High

880738

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.513

High

958374

ARP2
Actin-related protein 2

1

0

High-throughput

0.513

High

1276045

TPC11
Trafficking protein particle complex subunit 11

1

0

High-throughput

0.513

High

1316012

NRSN1
Neurensin-1

1

0

High-throughput

0.513

High

1331339

AL14E
ARL14 effector protein

1

0

High-throughput

0.513

High

1350955

DTX3L
E3 ubiquitin-protein ligase DTX3L

1

0

High-throughput

0.513

High

1399679

M4A10
Membrane-spanning 4-domains subfamily A member 10

1

0

High-throughput

0.513

High

1461090

MARF1
Meiosis regulator and mRNA stability factor 1

1

0

High-throughput

0.513

High

508810

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

10

High-throughput

0.501

High

952377

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

6

High-throughput

0.501

High

1417422

MLP3C
Microtubule-associated protein 1 light chain 3 gamma

1

6

High-throughput

0.501

High

1428413

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

6

High-throughput

0.501

High

1430359

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

6

High-throughput

0.501

High

1433233

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

6

High-throughput

0.501

High

505855

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

1

3

High-throughput

0.494

High

164470

NRP1
Neuropilin-1

1

1

High-throughput

0.479

High

180101

BET1
BET1 homolog

1

2

High-throughput

0.479

High

218937

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

226255

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

483254

CLCA
Clathrin light chain A

1

1

High-throughput

0.479

High

483416

CLCB
Clathrin light chain B

1

1

High-throughput

0.479

High

515741

TPC2B
Trafficking protein particle complex subunit 2B

1

1

High-throughput

0.479

High

520436

ANDR
Androgen receptor

1

4

Small-scale

0.479

High

540744

LAMP1
Lysosome-associated membrane glycoprotein 1

1

4

High-throughput

0.479

High

560552

IFM1
Interferon-induced transmembrane protein 1

1

3

High-throughput

0.479

High

704562

RXRB
Retinoic acid receptor RXR-beta

1

2

High-throughput

0.479

High

774701

BASI
Basigin

1

2

High-throughput

0.479

High

839106

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

Small-scale

0.479

High

845850

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.479

High

1031591

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.479

High

1108748

TBB3
Tubulin beta-3 chain

1

4

Small-scale

0.479

High

1142012

EEA1
Early endosome antigen 1

1

1

High-throughput

0.479

High

1233562

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1256032

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

1276365

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

1334615

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.479

High

1380686

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

1418508

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

1459255

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1461084

MYO6
Unconventional myosin-VI

1

2

High-throughput

0.479

High

1461092

TRAF6
TNF receptor-associated factor 6

1

2

Small-scale

0.479

High

731691

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

765103

CTNB1
Catenin beta-1

1

0

High-throughput

0.458

High

935273

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

1115137

CUL4A
Cullin-4A

1

0

High-throughput

0.458

High

1276942

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1366300

LPAR1
Lysophosphatidic acid receptor 1

1

0

Small-scale

0.458

High

352265

MBD3
Methyl-CpG-binding domain protein 3

1

1

Small-scale

0.445

High

515660

TPC2A
Trafficking protein particle complex subunit 2

1

1

High-throughput

0.445

High

1160792

DREB
Drebrin

1

2

High-throughput

0.445

High

1053464

FHI1A
FHF complex subunit HOOK-interacting protein 1A

1

1

High-throughput

0.437

High

1328733

FHI1B
FHF complex subunit HOOK-interacting protein 1B

1

1

High-throughput

0.437

High

261313

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.426

High

404947

PRIO
Major prion protein

1

0

High-throughput

0.426

High

1361034

P66B
Transcriptional repressor p66-beta

1

0

Small-scale

0.426

High

328186

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

6

High-throughput

0.408

High

94341

D6R9G5
Kelch like family member 2

1

5

High-throughput

0.407

High

1412905

PHAF1
Phagosome assembly factor 1

3

0

High-throughput

0.347

High

1396464

F167A
Protein FAM167A

2

0

High-throughput

0.328

High

1334371

IN80E
INO80 complex subunit E

2

0

High-throughput

0.310

High

1410549

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.282

High

1446683

LUC7L
Putative RNA-binding protein Luc7-like 1

1

0

High-throughput

0.282

High

1181356

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

1329711

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

0

High-throughput

0.279

Low

1331802

F133A
Protein FAM133A

1

0

High-throughput

0.279

Low

81739

EIFCL
Eukaryotic translation initiation factor 3 subunit C-like protein

1

0

High-throughput

0.249

Low

1293198

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025