Interactor 1: JADE2 (Q9NQC1)
E3 ubiquitin-protein ligase Jade-2 (EC 2.3.2.27) (Jade family PHD finger protein 2) (PHD finger protein 15)
Gene: JADE2
Interactor 2: BRPF3 (Q9ULD4)
Bromodomain and PHD finger-containing protein 3
Gene: BRPF3
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24981860 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PHD_2~zf-HC5HC2H_2, zf-HC5HC2H_2~zf-HC5HC2H_2 |
| Common GO terms | GO:0000123 - histone acetyltransferase complex GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0008270 - zinc ion binding |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025