Protein: IPSP
Plasma serine protease inhibitor (Acrosomal serine protease inhibitor) (Plasminogen activator inhibitor 3) (PAI-3) (PAI3) (Protein C inhibitor) (PCI) (Serpin A5)

Gene: IPSP, SERPINA5
Organism: Homo sapiens
Interactions: 63
UniProt ID: P05154

Gene Ontology (top 5):
GO:0001972 - retinoic acid binding
GO:0002020 - protease binding
GO:0002080 - acrosomal membrane
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005539 - glycosaminoglycan binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

397629

KLK3
Prostate-specific antigen

2

19

Small-scale

0.811

High

397654

HGFA
Hepatocyte growth factor activator

2

20

High-throughput

0.811

High

341480

UROK
Urokinase-type plasminogen activator

2

20

Small-scale

0.778

High

375826

PROC
Vitamin K-dependent protein C

2

20

Small-scale

0.755

High

341126

THRB
Prothrombin

1

20

Small-scale

0.647

High

341527

TPA
Tissue-type plasminogen activator

1

20

Small-scale

0.647

High

371455

FA11
Coagulation factor XI

1

20

Small-scale

0.647

High

371463

KLKB1
Plasma kallikrein

1

15

Small-scale

0.647

High

397632

ACRO
Acrosin

1

10

Small-scale

0.647

High

397631

FURIN
Furin

2

2

High-throughput

0.628

High

397660

TGO1
Transport and Golgi organization protein 1 homolog

2

8

High-throughput

0.628

High

397636

KLK2
Kallikrein-2

1

20

Small-scale

0.618

High

397656

EPS8
Epidermal growth factor receptor kinase substrate 8

2

3

High-throughput

0.576

High

195673

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

2

2

High-throughput

0.574

High

397661

HECD3
E3 ubiquitin-protein ligase HECTD3

2

2

High-throughput

0.574

High

397671

WWOX
WW domain-containing oxidoreductase

2

1

High-throughput

0.574

High

397674

FBX2
F-box only protein 2

2

5

High-throughput

0.574

High

362674

FINC
Fibronectin

1

5

Small-scale

0.569

High

397641

CALX
Calnexin

1

2

High-throughput

0.536

High

397638

CBL
E3 ubiquitin-protein ligase CBL

2

1

High-throughput

0.526

High

397645

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.515

High

397673

BAP29
B-cell receptor-associated protein 29

1

1

High-throughput

0.515

High

201509

DHH
Desert hedgehog protein

1

0

High-throughput

0.513

High

397662

CSN6
COP9 signalosome complex subunit 6

1

1

High-throughput

0.494

High

397664

PIAS4
E3 SUMO-protein ligase PIAS4

1

1

High-throughput

0.494

High

397669

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

1

High-throughput

0.494

High

170772

PGRC2
Membrane-associated progesterone receptor component 2

1

0

High-throughput

0.493

High

397659

MSMO1
Methylsterol monooxygenase 1

1

0

High-throughput

0.493

High

263141

SC22B
Vesicle-trafficking protein SEC22b

1

1

High-throughput

0.470

High

397646

RIDA
2-iminobutanoate/2-iminopropanoate deaminase

1

0

High-throughput

0.460

High

73006

B4DTH2
Fibronectin

1

5

Small-scale

0.445

High

397630

HS90A
Heat shock protein HSP 90-alpha

1

4

Small-scale

0.445

High

397637

FLNA
Filamin-A

1

1

Small-scale

0.445

High

397657

PLEC
Plectin

1

1

Small-scale

0.445

High

397665

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

1

Small-scale

0.445

High

397668

MIA2
Melanoma inhibitory activity protein 2

1

7

High-throughput

0.445

High

373509

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.437

High

124554

CLIC1
Chloride intracellular channel protein 1

1

0

Small-scale

0.426

High

376407

APOB
Apolipoprotein B-100

1

0

Small-scale

0.426

High

388148

HSPB1
Heat shock protein beta-1

1

0

Small-scale

0.426

High

397633

RS2
Small ribosomal subunit protein uS5

1

0

Small-scale

0.426

High

397635

RL7
Large ribosomal subunit protein uL30

1

0

Small-scale

0.426

High

397639

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.426

High

397640

RL13
Large ribosomal subunit protein eL13

1

0

Small-scale

0.426

High

397642

PRDX6
Peroxiredoxin-6

1

0

Small-scale

0.426

High

397643

CAPZB
F-actin-capping protein subunit beta

1

0

Small-scale

0.426

High

397647

IF6
Eukaryotic translation initiation factor 6

1

0

Small-scale

0.426

High

397648

RS8
Small ribosomal subunit protein eS8

1

0

Small-scale

0.426

High

397649

RS6
Small ribosomal subunit protein eS6

1

0

Small-scale

0.426

High

397650

RL10A
Large ribosomal subunit protein uL1

1

0

Small-scale

0.426

High

397651

RL8
Large ribosomal subunit protein uL2

1

0

Small-scale

0.426

High

397653

CLH1
Clathrin heavy chain 1

1

0

Small-scale

0.426

High

397655

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.417

High

242645

IF2P
Eukaryotic translation initiation factor 5B

1

1

Small-scale

0.407

High

397644

MCM2
DNA replication licensing factor MCM2

1

5

Small-scale

0.407

High

397670

XPO5
Exportin-5

1

1

Small-scale

0.407

High

397667

ESIP1
Epithelial-stromal interaction protein 1

2

0

High-throughput

0.328

High

397634

H15
Histone H1.5

1

0

High-throughput

0.269

Low

397652

SERB
Phosphoserine phosphatase

1

0

Small-scale

0.232

Low

397658

SF3B3
Splicing factor 3B subunit 3

1

0

Small-scale

0.232

Low

397663

CCAR2
Cell cycle and apoptosis regulator protein 2

1

0

Small-scale

0.232

Low

397666

RENT1
Regulator of nonsense transcripts 1

1

0

Small-scale

0.232

Low

397672

SYLC
Leucine--tRNA ligase, cytoplasmic

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024