HitPredict

Interactor 1: NXF1 (Q9U1H9)
Nuclear RNA export factor 1 (Protein small bristles) (Protein tip-associating)
Gene: sbr

Interactor 2: NXT1 (Q9V3H8)
NTF2-related export protein (p15)
Gene: NXT1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	1.00	0.945

Property	Details
Experiments	18086857, 31398345, 31570835, 22036573, 38944040, unassigned4
Identification Methods	affinity chromatography technology, x-ray crystallography, pull down, two hybrid, anti tag coimmunoprecipitation, experimental interaction detection
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	NTF2~NXF_NTF2
Common GO terms	GO:0005634 - nucleus GO:0005635 - nuclear envelope GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016973 - poly(A)+ mRNA export from nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 672 Dm			1 133
+	Hs
		1446577 NXF1_HUMAN (3-672): 0: 732: 29.11		NXT2_HUMAN (4-132): 2.61e-48: 153: 42.11
+	Hs
		1458762 NXF1_HUMAN (3-672): 0: 732: 29.11		NXT1_HUMAN (4-132): 2.17e-48: 153: 41.35
+	Hs
		1101077 NXF1_HUMAN (3-672): 0: 732: 29.11		G3BP1_HUMAN (10-132): 1.72e-42: 147: 20.59
+	Mm
		1190601 NXF1_MOUSE (3-672): 0: 722: 28.09		NXT2_MOUSE (1-132): 9.43e-49: 154: 39.71
+	Mm
		1408747 NXF1_MOUSE (3-672): 0: 722: 28.09		NXT1_MOUSE (4-132): 3.33e-48: 153: 40.60
+	Hs
		965590 NXF1_HUMAN (3-672): 0: 732: 29.11		NTF2_HUMAN (13-130): 1.75e-40: 133: 27.50
+	Hs
		1429100 NXF2_HUMAN (2-672): 0: 700: 25.76		NXT2_HUMAN (4-132): 2.61e-48: 153: 42.11
+	Hs
		1429109 NXF2_HUMAN (2-672): 0: 700: 25.76		NXT1_HUMAN (4-132): 2.17e-48: 153: 41.35
+	Hs
		1433500 NXF3_HUMAN (13-564): 0: 573: 21.53		NXT2_HUMAN (4-132): 2.61e-48: 153: 42.11
+	Hs
		1433503 NXF3_HUMAN (13-564): 0: 573: 21.53		NXT1_HUMAN (4-132): 2.17e-48: 153: 41.35
+	Mm
		1190600 Q8R499_MOUSE (18-671): 0: 562: 20.24		NXT2_MOUSE (1-132): 9.43e-49: 154: 39.71
+	Mm
		1341585 Q8R499_MOUSE (18-671): 0: 562: 20.24		NXT1_MOUSE (4-132): 3.33e-48: 153: 40.60
+	Ce
		1458100 NXF1_CAEEL (121-670): 1.53e-150: 452: 22.24		NXT1_CAEEL (2-132): 5.63e-42: 137: 28.79
+	Dm
		1305559 Q8IQK4_DROME (106-616): 1.51e-125: 387: 22.35		NXT1_DROME (1-133): 1.32e-46: 148: 100.00
+	Ce
		1458101 NXF2_CAEEL (198-547): 8.92e-110: 339: 20.60		NXT1_CAEEL (2-132): 5.63e-42: 137: 28.79
+	Mm
		1190598 Q4ZGD9_MOUSE (596-672): 1.61e-16: 85: 28.57		NXT2_MOUSE (1-132): 9.43e-49: 154: 39.71
+	Mm
		1197227 Q4ZGD9_MOUSE (596-672): 1.61e-16: 85: 28.57		NXT1_MOUSE (4-132): 3.33e-48: 153: 40.60
+	Dm
		1463641 NXF2_DROME (102-344): 9.32e-14: 76.9: 18.08		NXT1_DROME (1-133): 1.32e-46: 148: 100.00