Interactor 1: CLD4 (O14493)
Claudin-4 (Clostridium perfringens enterotoxin receptor) (CPE-R) (CPE-receptor) (Williams-Beuren syndrome chromosomal region 8 protein)
Gene: CLDN4

Interactor 2: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 36237976
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004888 - transmembrane signaling receptor activity
GO:0005886 - plasma membrane
GO:0016324 - apical plasma membrane
GO:0030335 - positive regulation of cell migration
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 209
Hs

1 2555
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024