HitPredict

Interactor 1: PCDA7 (Q9UN72)
Protocadherin alpha-7 (PCDH-alpha-7)
Gene: PCDHA7

Interactor 2: PCDA8 (Q9Y5H6)
Protocadherin alpha-8 (PCDH-alpha-8)
Gene: PCDHA8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cadherin~Cadherin, Cadherin~Cadherin_2
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules GO:0007399 - nervous system development
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 937 Hs			1 950
+	Hs
		1462189 PCDA7_HUMAN (1-937): 0: 1067: 100.00		PCDA4_HUMAN (1-950): 0: 1109: 80.95
+	Hs
		1462193 PCDA7_HUMAN (1-937): 0: 1067: 100.00		PCDA2_HUMAN (1-950): 0: 1106: 79.58
+	Hs
		1491674 PCDA2_HUMAN (1-937): 0: 1048: 80.17		PCDA8_HUMAN (1-950): 0: 1125: 100.00
+	Hs
		1462205 PCDA4_HUMAN (1-937): 0: 1046: 85.32		PCDA8_HUMAN (1-950): 0: 1125: 100.00
+	Hs
		1491675 PCDAD_HUMAN (1-937): 0: 1040: 80.84		PCDA8_HUMAN (1-950): 0: 1125: 100.00
+	Hs
		1462208 PCDA4_HUMAN (1-937): 0: 1046: 85.32		PCDA1_HUMAN (1-950): 0: 1109: 81.05
+	Hs
		1462206 PCDA4_HUMAN (1-937): 0: 1046: 85.32		PCDAB_HUMAN (1-950): 0: 1105: 81.47
+	Hs
		1462194 PCDA7_HUMAN (1-937): 0: 1067: 100.00		PCDAA_HUMAN (4-950): 0: 1081: 81.73
+	Hs
		1462191 PCDA7_HUMAN (1-937): 0: 1067: 100.00		PCDA9_HUMAN (24-950): 0: 1079: 81.12
+	Hs
		1462190 PCDA7_HUMAN (1-937): 0: 1067: 100.00		PCDAC_HUMAN (1-950): 0: 1066: 80.74
+	Hs
		1491680 PCDA5_HUMAN (24-937): 0: 1051: 83.26		PCDAA_HUMAN (4-950): 0: 1081: 81.73
+	Hs
		1491684 PCDA2_HUMAN (1-937): 0: 1048: 80.17		PCDAA_HUMAN (4-950): 0: 1081: 81.73
+	Hs
		1462207 PCDA4_HUMAN (1-937): 0: 1046: 85.32		PCDAA_HUMAN (4-950): 0: 1081: 81.73
+	Hs
		1462204 PCDA4_HUMAN (1-937): 0: 1046: 85.32		PCDA9_HUMAN (24-950): 0: 1079: 81.12
+	Hs
		1491685 PCDAD_HUMAN (1-937): 0: 1040: 80.84		PCDAA_HUMAN (4-950): 0: 1081: 81.73
+	Hs
		1462201 PCDA4_HUMAN (1-937): 0: 1046: 85.32		PCDAC_HUMAN (1-950): 0: 1066: 80.74
+	Hs
		1462161 PCDA4_HUMAN (1-937): 0: 1046: 85.32		PCDGK_HUMAN (27-898): 0: 958: 39.53
+	Hs
		1462203 PCDA4_HUMAN (1-937): 0: 1046: 85.32		PCDGA_HUMAN (2-342): 6.23e-63: 232: 22.51