Protein: PCDGK
Protocadherin gamma-C3 (PCDH-gamma-C3) (Protocadherin-2) (Protocadherin-43) (PC-43)

Gene: PCDGK, PCDHGC3
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q9UN70

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007399 - nervous system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1462169

PCDGD
Protocadherin gamma-B1

3

20

High-throughput

0.855

High

556423

CADH1
Cadherin-1

2

20

High-throughput

0.811

High

1446364

PCD12
Protocadherin-12

2

19

High-throughput

0.811

High

1462161

PCDA4
Protocadherin alpha-4

2

20

High-throughput

0.811

High

1462167

PCDGF
Protocadherin gamma-B3

2

20

High-throughput

0.811

High

1462168

PCDGE
Protocadherin gamma-B2

2

20

High-throughput

0.776

High

1462170

PCDG6
Protocadherin gamma-A6

2

20

High-throughput

0.776

High

1186243

CEA21
Cell adhesion molecule CEACAM21

3

2

High-throughput

0.770

High

275824

CAD16
Cadherin-16

1

20

High-throughput

0.691

High

1088178

CAD17
Cadherin-17

1

20

High-throughput

0.691

High

1462061

CLC4A
C-type lectin domain family 4 member A

1

6

High-throughput

0.691

High

1462165

PCDB6
Protocadherin beta-6

1

20

High-throughput

0.691

High

1462172

PCDG4
Protocadherin gamma-A4

1

20

High-throughput

0.691

High

440787

FYN
Tyrosine-protein kinase Fyn

2

6

High-throughput

0.628

High

557525

SRC
Proto-oncogene tyrosine-protein kinase Src

2

6

High-throughput

0.628

High

618493

GNAZ
Guanine nucleotide-binding protein G(z) subunit alpha

2

1

High-throughput

0.628

High

659067

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

2

15

High-throughput

0.628

High

1088171

CNTN1
Contactin-1

2

5

High-throughput

0.628

High

1187229

CC50B
Cell cycle control protein 50B

2

4

High-throughput

0.628

High

1431497

SPTN4
Spectrin beta chain, non-erythrocytic 4

2

1

High-throughput

0.628

High

1453618

FLRT1
Leucine-rich repeat transmembrane protein FLRT1

2

5

High-throughput

0.628

High

1397316

CB048
Putative uncharacterized protein C2orf48

3

1

High-throughput

0.609

High

607320

NEUM
Neuromodulin

2

0

High-throughput

0.602

High

1215654

GRTP1
Growth hormone-regulated TBC protein 1

2

0

High-throughput

0.602

High

1273113

EEPD1
Endonuclease/exonuclease/phosphatase family domain-containing protein 1

2

0

High-throughput

0.602

High

1446234

NRN1
Neuritin

2

0

High-throughput

0.602

High

1451256

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

2

0

High-throughput

0.602

High

1330147

PCD20
Protocadherin-20

1

20

High-throughput

0.575

High

1462163

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

3

High-throughput

0.575

High

1462166

PCDGH
Protocadherin gamma-B5

1

20

High-throughput

0.575

High

1462171

PCDG5
Protocadherin gamma-A5

1

20

High-throughput

0.575

High

1462173

PCDA8
Protocadherin alpha-8

1

20

High-throughput

0.575

High

1382401

SPSB4
SPRY domain-containing SOCS box protein 4

2

17

High-throughput

0.549

High

1439678

XAGE1
X antigen family member 1

2

1

High-throughput

0.549

High

596546

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.546

High

375015

RASH
GTPase HRas

1

3

High-throughput

0.536

High

463260

YES
Tyrosine-protein kinase Yes

1

6

High-throughput

0.536

High

761309

RYK
Tyrosine-protein kinase RYK

1

17

High-throughput

0.536

High

893543

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

1

High-throughput

0.536

High

1438494

RXFP1
Relaxin receptor 1

1

1

High-throughput

0.536

High

1459588

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

1

2

High-throughput

0.536

High

1389673

MFSD3
Major facilitator superfamily domain-containing protein 3

1

0

High-throughput

0.518

High

1068335

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.513

High

1251524

CD109
CD109 antigen

1

0

High-throughput

0.513

High

1461204

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

0

High-throughput

0.513

High

1462162

EPCR
Endothelial protein C receptor

1

0

High-throughput

0.513

High

423454

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

1329942

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.489

High

412804

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.479

High

1448852

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.479

High

156377

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

2

High-throughput

0.470

High

139345

UPK2
Uroplakin-2

1

14

High-throughput

0.445

High

634818

GRAH
Granzyme H

1

1

High-throughput

0.445

High

860055

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.445

High

914504

EFNB2
Ephrin-B2

1

6

High-throughput

0.445

High

1010126

DLK1
Protein delta homolog 1

1

3

High-throughput

0.445

High

1242973

S39A4
Zinc transporter ZIP4

1

4

High-throughput

0.445

High

1273827

NIPA1
Magnesium transporter NIPA1

1

1

High-throughput

0.445

High

1310982

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

6

High-throughput

0.445

High

1346834

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

6

High-throughput

0.445

High

1461544

S39AA
Zinc transporter ZIP10

1

4

High-throughput

0.445

High

1419267

TRI54
Tripartite motif-containing protein 54

1

4

High-throughput

0.439

High

652598

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

1

High-throughput

0.437

High

946907

H2B1D
Histone H2B type 1-D

1

20

High-throughput

0.437

High

1256086

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

388469

B3AT
Band 3 anion transport protein

1

0

High-throughput

0.426

High

1208682

NTCP5
Sodium/bile acid cotransporter 5

1

0

High-throughput

0.426

High

1291712

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.426

High

1453248

GPC5B
G-protein coupled receptor family C group 5 member B

1

0

High-throughput

0.426

High

1239567

ZNT6
Zinc transporter 6

1

6

High-throughput

0.407

High

1391530

BSCL2
Seipin

1

1

High-throughput

0.407

High

1462164

KLK5
Kallikrein-5

1

5

High-throughput

0.407

High

1405965

CDCA3
Cell division cycle-associated protein 3

2

0

High-throughput

0.328

High

1372497

HGD
Homogentisate 1,2-dioxygenase

1

0

High-throughput

0.282

High

1243107

ERIC5
Glutamate-rich protein 5

1

0

High-throughput

0.279

Low

1357062

UBTD2
Ubiquitin domain-containing protein 2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025