HitPredict

Interactor 1: SOCS2 (O14508)
Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2)
Gene: SOCS2

Interactor 2: PELP1 (Q8IZL8)
Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor) (Transcription factor HMX3)
Gene: PELP1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24752897
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 198 Hs			1 1130
+	Hs
		523059 SRC_HUMAN (1-176): 2.1e-43: 153: 15.76		PELP1_HUMAN (1-1130): 0: 788: 100.00
+	Rn
		1122684 SRC_RAT (1-176): 1.42e-43: 154: 15.76		PELP1_RAT (1-1130): 0: 668: 81.44
+	Rn
		1122683 P85A_RAT (14-161): 1.32e-14: 73.2: 18.54		PELP1_RAT (1-1130): 0: 668: 81.44
+	Hs
		442866 HCK_HUMAN (14-172): 3.69e-44: 155: 14.97		CBP_HUMAN (631-1010): 2.14e-28: 126: 16.87
+	Hs
		523092 SRC_HUMAN (1-176): 2.1e-43: 153: 15.76		CBP_HUMAN (631-1010): 2.14e-28: 126: 16.87
+	Hs
		522749 SRC_HUMAN (1-176): 2.1e-43: 153: 15.76		MUC1_HUMAN (443-1092): 6.43e-28: 124: 11.79
+	Hs
		337335 ABL1_HUMAN (3-173): 4.38e-42: 152: 19.65		MUC1_HUMAN (443-1092): 6.43e-28: 124: 11.79
+	Hs
		411582 LCK_HUMAN (1-172): 3.23e-43: 152: 15.63		MUC1_HUMAN (443-1092): 6.43e-28: 124: 11.79
+	Hs
		433930 LYN_HUMAN (14-172): 3.22e-41: 147: 15.57		CBP_HUMAN (631-1010): 2.14e-28: 126: 16.87
+	Hs
		433560 LYN_HUMAN (14-172): 3.22e-41: 147: 15.57		MUC1_HUMAN (443-1092): 6.43e-28: 124: 11.79
+	Hs
		411823 LCK_HUMAN (1-172): 3.23e-43: 152: 15.63		ASPP1_HUMAN (617-1076): 6.49e-23: 108: 15.50
+	Hs
		433948 LYN_HUMAN (14-172): 3.22e-41: 147: 15.57		ASPP1_HUMAN (617-1076): 6.49e-23: 108: 15.50
+	Hs
		297808 LYN_HUMAN (14-172): 3.22e-41: 147: 15.57		K0754_HUMAN (443-751): 1.25e-14: 81.6: 13.97
+	Mm
		101424 LYN_MOUSE (14-172): 1.34e-41: 148: 14.97		F8VPR5_MOUSE (679-1121): 6.98e-14: 78.9: 11.49
+	Hs
		64077 SRC_HUMAN (1-176): 2.1e-43: 153: 15.76		L37A2_HUMAN (602-1129): 5.6e-12: 72.8: 12.80
+	Hs
		522942 SRC_HUMAN (1-176): 2.1e-43: 153: 15.76		EP300_HUMAN (697-1081): 1.18e-11: 71.5: 11.17
+	Hs
		411694 LCK_HUMAN (1-172): 3.23e-43: 152: 15.63		EP300_HUMAN (697-1081): 1.18e-11: 71.5: 11.17
+	Hs
		203198 LCK_HUMAN (1-172): 3.23e-43: 152: 15.63		SYNJ1_HUMAN (406-844): 2.09e-10: 67.4: 12.61
+	Hs
		655342 P85A_HUMAN (14-161): 1.06e-14: 73.6: 18.54		EP300_HUMAN (697-1081): 1.18e-11: 71.5: 11.17
+	Hs
		655449 P85A_HUMAN (14-161): 1.06e-14: 73.6: 18.54		MINT_HUMAN (731-1119): 1.09e-10: 68.5: 12.18