HitPredict

Interactor 1: Q9VAY6 (Q9VAY6)
Pre-mRNA-splicing factor SPF27
Gene: BCAS2

Interactor 2: Q9VYQ9 (Q9VYQ9)
Pleiotropic regulator 1
Gene: Tango4

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0000974 - Prp19 complex GO:0071011 - precatalytic spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 278 Dm			1 482
+	At
		1192511 SPF27_ARATH (2-209): 1.34e-80: 245: 28.91		PRL1_ARATH (3-474): 1.91e-99: 308: 46.86
+	Hs
		222406 SPF27_HUMAN (1-206): 1.32e-97: 287: 59.71		PLRG1_HUMAN (58-366): 9.03e-71: 235: 16.67
+	Hs
		298047 SPF27_HUMAN (1-206): 1.32e-97: 287: 59.71		SNR40_HUMAN (18-324): 5.42e-71: 231: 18.04
+	Hs
		298045 SPF27_HUMAN (1-206): 1.32e-97: 287: 59.71		FBXW7_HUMAN (40-279): 8.74e-37: 145: 16.53
+	Hs
		297951 SPF27_HUMAN (1-206): 1.32e-97: 287: 59.71		WDR5_HUMAN (1-200): 1.29e-23: 103: 13.59