HitPredict

Interactor 1: CDKA1 (O14519)
Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1) (Deleted in oral cancer 1) (DOC-1) (Putative oral cancer suppressor)
Gene: CDK2AP1

Interactor 2: MBD2 (Q9UBB5)
Methyl-CpG-binding domain protein 2 (Demethylase) (DMTase) (Methyl-CpG-binding protein MBD2)
Gene: MBD2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	24981860, 26496610, 33961781, 20523938, 25123934
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016581 - NuRD complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 115 Hs			1 411
+	Hs
		279819 CDKA2_HUMAN (19-115): 6.1e-40: 131: 66.00		MBD2_HUMAN (1-411): 0: 613: 100.00
+	Hs
		146786 CDKA1_HUMAN (1-115): 1.29e-60: 183: 100.00		MBD3_HUMAN (148-397): 4.14e-148: 423: 76.00
+	Hs
		279784 CDKA2_HUMAN (19-115): 6.1e-40: 131: 66.00		MBD3_HUMAN (148-397): 4.14e-148: 423: 76.00
+	Hs
		146845 CDKA1_HUMAN (1-115): 1.29e-60: 183: 100.00		MB3L1_HUMAN (218-397): 4.54e-80: 246: 41.76
+	Dm
		115162 M9PEA2_DROME (37-114): 1.29e-26: 101: 58.97		Q9VHB7_DROME (236-387): 8.97e-59: 196: 45.86