HitPredict

Interactor 1: GLSK (D3Z7P3)
Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2) [Cleaved into: Glutaminase kidney isoform, mitochondrial 68 kDa chain; Glutaminase kidney isoform, mitochondrial 65 kDa chain]
Gene: Gls

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	28469556
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ank_2~Ank_2, Ank_2~EF-hand_14, Ank_2~Glutaminase
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 674 Mm			1 1730
+	Mm
		103600 ANK3_MOUSE (493-670): 2e-34: 143: 14.78		SHAN3_MOUSE (1-1730): 0: 626: 100.00
+	Hs
		862070 MIB1_HUMAN (323-673): 2.6e-49: 187: 13.28		DAPK1_HUMAN (17-450): 1.03e-87: 318: 15.97
+	Mm
		103591 ANK3_MOUSE (493-670): 2e-34: 143: 14.78		ANK3_MOUSE (41-592): 7.79e-85: 311: 15.58
+	Hs
		1329533 TNKS2_HUMAN (492-670): 6.44e-32: 134: 14.57		TNKS2_HUMAN (1-544): 1.02e-87: 315: 15.16
+	Mm
		1193396 MIB1_MOUSE (323-673): 4.46e-49: 187: 13.28		DAPK1_MOUSE (103-578): 1.89e-68: 257: 13.99
+	Hs
		862012 DAPK1_HUMAN (349-644): 3.64e-27: 120: 15.39		DAPK1_HUMAN (17-450): 1.03e-87: 318: 15.97
+	Hs
		1206048 MIB1_HUMAN (323-673): 2.6e-49: 187: 13.28		Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21
+	Hs
		883555 MIB1_HUMAN (323-673): 2.6e-49: 187: 13.28		RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21
+	Hs
		1021462 ANK3_HUMAN (380-672): 2.27e-45: 177: 13.99		Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21
+	Hs
		883496 ANK3_HUMAN (380-672): 2.27e-45: 177: 13.99		RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21
+	Mm
		1193395 MIB1_MOUSE (323-673): 4.46e-49: 187: 13.28		MIB1_MOUSE (187-684): 8.82e-51: 198: 10.36
+	Hs
		1205972 MIB1_HUMAN (323-673): 2.6e-49: 187: 13.28		MIB1_HUMAN (187-625): 7.14e-50: 195: 10.66
+	Hs
		166919 ANK3_HUMAN (380-672): 2.27e-45: 177: 13.99		ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60
+	Hs
		167014 TNKS2_HUMAN (492-670): 6.44e-32: 134: 14.57		ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60
+	Hs
		166969 ANR44_HUMAN (516-670): 1.31e-28: 124: 15.96		ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60
+	Hs
		166913 ANK2_HUMAN (545-671): 4.45e-26: 117: 22.05		ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60
+	Hs
		862028 DAPK1_HUMAN (349-644): 3.64e-27: 120: 15.39		ANK2_HUMAN (212-349): 7.67e-29: 129: 24.64
+	Dr
		1193376 MIB1_DANRE (276-632): 3.72e-29: 126: 10.78		MIB1_DANRE (129-324): 1.65e-14: 81.6: 32.50
+	Mm
		103608 ANK3_MOUSE (493-670): 2e-34: 143: 14.78		ANK2_MOUSE (134-335): 6.85e-09: 63.5: 31.19