HitPredict

Interactor 1: GOSR1 (Q9VE50)
Golgi SNAP receptor complex member 1 (Probable 28 kDa Golgi SNARE protein)
Gene: Gos28

Interactor 2: Q9VVX6 (Q9VVX6)
BET1 homolog (Golgi vesicular membrane-trafficking protein p18)
Gene: Bet1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.812

Property	Details
Experiments	22036573, 19079254, 38944040
Identification Methods	affinity chromatography technology, two hybrid array, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~V-SNARE_C
Common GO terms	GO:0000139 - Golgi membrane GO:0005484 - SNAP receptor activity GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0015031 - protein transport GO:0031201 - SNARE complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 232 Dm			1 117
+	Rn
		1224309 GOSR1_RAT (3-232): 7.73e-88: 261: 45.12		BET1_RAT (7-117): 1.19e-36: 122: 36.94
+	Hs
		179779 GOSR1_HUMAN (3-232): 9.11e-88: 261: 45.53		BET1_HUMAN (10-117): 1.08e-36: 122: 39.82
+	Rn
		204385 GOSR1_RAT (3-232): 7.73e-88: 261: 45.12		BET1L_RAT (19-114): 1.71e-24: 91.3: 29.90
+	Hs
		331924 GOSR1_HUMAN (3-232): 9.11e-88: 261: 45.53		BET1L_HUMAN (20-114): 3.44e-24: 90.5: 31.25
+	Hs
		225896 GOSR1_HUMAN (3-232): 9.11e-88: 261: 45.53		STX6_HUMAN (8-100): 1.41e-19: 82.4: 22.58
+	Hs
		96842 E9PCW1_HUMAN (3-232): 2.16e-87: 260: 45.49		STX6_HUMAN (8-100): 1.41e-19: 82.4: 22.58
+	Sc
		652922 GOSR1_YEAST (5-228): 3.73e-67: 208: 22.03		BET1_YEAST (17-114): 7.25e-25: 93.2: 21.43
+	Sc
		803086 GOSR1_YEAST (5-228): 3.73e-67: 208: 22.03		SFT1_YEAST (19-116): 2.56e-21: 82.8: 19.39