HitPredict

Interactor 1: SOCS6 (O14544)
Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4)
Gene: SOCS6

Interactor 2: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12052866
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 535 Hs			1 445
+	Hs
		411549 LCK_HUMAN (258-495): 3.81e-54: 192: 17.20		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		411668 LCK_HUMAN (258-495): 3.81e-54: 192: 17.20		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		427991 SRC_HUMAN (257-495): 1.3e-50: 183: 15.48		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		428098 BLK_HUMAN (301-495): 4.58e-47: 173: 16.13		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Dm
		337680 SRC64_DROME (278-511): 7.3e-46: 170: 16.53		TBB1_DROME (1-429): 0: 709: 97.67
+	Hs
		381102 LYN_HUMAN (292-495): 1.72e-46: 171: 14.82		TBB4A_HUMAN (1-427): 0: 706: 98.60
+	Hs
		181767 SOCS1_HUMAN (379-535): 5.8e-42: 151: 26.75		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		181840 SOCS1_HUMAN (379-535): 5.8e-42: 151: 26.75		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		181757 SOCS1_HUMAN (379-535): 5.8e-42: 151: 26.75		TBB4A_HUMAN (1-427): 0: 706: 98.60
+	Hs
		129166 P85B_HUMAN (380-491): 1.89e-14: 78.2: 27.68		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		129330 P85B_HUMAN (380-491): 1.89e-14: 78.2: 27.68		TBB6_HUMAN (1-432): 0: 706: 92.36