Protein: DPYL3
Dihydropyrimidinase-related protein 3 (DRP-3) (Collapsin response mediator protein 4) (CRMP-4) (Unc-33-like phosphoprotein 1) (ULIP-1)

Gene: DPYL3, DPYSL3
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q14195

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0010976 - positive regulation of neuron projection development
GO:0010977 - negative regulation of neuron projection development
GO:0016812 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1123248

DPYL2
Dihydropyrimidinase-related protein 2

10

17

High-throughput

0.978

High

1123192

DPYL1
Dihydropyrimidinase-related protein 1

5

17

High-throughput

0.936

High

1123272

DPYL5
Dihydropyrimidinase-related protein 5

4

16

High-throughput

0.902

High

155851

DPYL4
Dihydropyrimidinase-related protein 4

3

18

High-throughput

0.855

High

1120598

DPYS
Dihydropyrimidinase

2

16

High-throughput

0.811

High

124339

HAX1
HCLS1-associated protein X-1

3

5

High-throughput

0.667

High

1123249

DGUOK
Deoxyguanosine kinase, mitochondrial

3

4

High-throughput

0.667

High

1123252

BOREA
Borealin

3

2

High-throughput

0.667

High

1123280

KTU
Protein kintoun

3

5

High-throughput

0.667

High

1123281

ARMC1
Armadillo repeat-containing protein 1

3

3

High-throughput

0.667

High

1123282

NUFP1
FMR1-interacting protein NUFIP1

3

4

High-throughput

0.609

High

1123287

RRP7A
Ribosomal RNA-processing protein 7 homolog A

3

2

High-throughput

0.609

High

1123278

DISC1
Disrupted in schizophrenia 1 protein

2

2

High-throughput

0.590

High

241662

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

1123284

TNIK
TRAF2 and NCK-interacting protein kinase

2

6

High-throughput

0.576

High

289148

PRDM1
PR domain zinc finger protein 1

2

1

High-throughput

0.574

High

1123257

OTU6A
OTU domain-containing protein 6A

2

1

High-throughput

0.553

High

529785

TAU
Microtubule-associated protein tau

1

10

High-throughput

0.536

High

906884

GPM6A
Neuronal membrane glycoprotein M6-a

1

4

High-throughput

0.536

High

966307

1433G
14-3-3 protein gamma

1

7

High-throughput

0.536

High

1049285

1433F
14-3-3 protein eta

1

7

High-throughput

0.536

High

1095372

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

2

High-throughput

0.536

High

1123259

FANCM
Fanconi anemia group M protein

1

1

High-throughput

0.536

High

1123261

TTLL6
Tubulin polyglutamylase TTLL6

1

1

High-throughput

0.536

High

1123264

ARI1B
AT-rich interactive domain-containing protein 1B

1

2

High-throughput

0.536

High

1123273

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

8

High-throughput

0.536

High

830721

CCNF
Cyclin-F

1

3

High-throughput

0.515

High

1123276

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.513

High

1123254

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.501

High

667302

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.489

High

1123271

EYA1
Protein phosphatase EYA1

1

2

High-throughput

0.489

High

132030

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

8

High-throughput

0.479

High

411918

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.479

High

457436

TBB5
Tubulin beta chain

1

7

High-throughput

0.479

High

651324

CBL
E3 ubiquitin-protein ligase CBL

1

5

High-throughput

0.479

High

667844

CDK2
Cyclin-dependent kinase 2

1

3

High-throughput

0.479

High

862127

YAP1
Transcriptional coactivator YAP1

1

13

High-throughput

0.479

High

888056

MCM2
DNA replication licensing factor MCM2

1

5

High-throughput

0.479

High

970482

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

995586

ACTC
Actin, alpha cardiac muscle 1

1

4

High-throughput

0.479

High

1026375

HSF1
Heat shock factor protein 1

1

2

High-throughput

0.479

High

1047413

K1C17
Keratin, type I cytoskeletal 17

1

2

High-throughput

0.479

High

1100770

G3BP1
Ras GTPase-activating protein-binding protein 1

1

4

High-throughput

0.479

High

1113086

CUL3
Cullin-3

1

3

High-throughput

0.479

High

1115646

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.479

High

1123247

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.479

High

1123255

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1123256

TBA1A
Tubulin alpha-1A chain

1

13

High-throughput

0.479

High

1123258

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1123262

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1123265

BICD2
Protein bicaudal D homolog 2

1

5

High-throughput

0.479

High

1123266

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1123269

SPDLY
Protein Spindly

1

4

High-throughput

0.479

High

1123285

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.479

High

1123251

TKFC
Triokinase/FMN cyclase

1

0

High-throughput

0.458

High

705334

GRN
Progranulin

1

2

High-throughput

0.445

High

765503

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

934600

TERA
Transitional endoplasmic reticulum ATPase

1

10

High-throughput

0.445

High

1123286

ITM2B
Integral membrane protein 2B

1

4

High-throughput

0.445

High

105923

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

218173

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

372006

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.437

High

1123260

F186B
Protein FAM186B

1

1

High-throughput

0.437

High

1123274

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

1123270

S45A3
Solute carrier family 45 member 3

1

1

High-throughput

0.407

High

1123275

VIAAT
Vesicular inhibitory amino acid transporter

1

1

High-throughput

0.407

High

1123250

KIZ
Centrosomal protein kizuna

2

0

High-throughput

0.328

High

1123267

ACD
Adrenocortical dysplasia protein homolog

1

0

High-throughput

0.299

High

928445

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.288

High

1123279

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.288

High

647463

UD11
UDP-glucuronosyltransferase 1A1

1

0

High-throughput

0.279

Low

1083100

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.279

Low

1123253

PPM1J
Protein phosphatase 1J

1

0

High-throughput

0.279

Low

1123263

ZN248
Zinc finger protein 248

1

0

High-throughput

0.279

Low

1123283

RWD2A
RWD domain-containing protein 2A

1

0

High-throughput

0.279

Low

1123288

NGN3
Neurogenin-3

1

0

High-throughput

0.279

Low

1123268

CC049
Putative uncharacterized protein C3orf49

1

0

High-throughput

0.249

Low

1123277

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.249

Low

587080

ITF2
Transcription factor 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025