HitPredict

Interactor 1: DC1I1 (O14576)
Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1)
Gene: DYNC1I1

Interactor 2: STAU1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1
Gene: STAU1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	15303970, 15121898
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0036464 - cytoplasmic ribonucleoprotein granule
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 645 Hs			1 577
+	Hs
		322573 DC1I2_HUMAN (1-645): 4.95e-134: 408: 74.88		STAU1_HUMAN (1-577): 0: 524: 100.00
+	Hs
		323214 NLE1_HUMAN (195-605): 1.31e-84: 275: 15.79		STAU1_HUMAN (1-577): 0: 524: 100.00
+	Hs
		322417 WDR5_HUMAN (135-467): 5.01e-40: 151: 11.18		STAU1_HUMAN (1-577): 0: 524: 100.00
+	Hs
		877337 FBXW7_HUMAN (4-601): 3.88e-73: 251: 12.71		DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57
+	Hs
		944964 NLE1_HUMAN (195-605): 1.31e-84: 275: 15.79		RED1_HUMAN (254-488): 1.1e-31: 132: 17.92
+	Hs
		269908 NLE1_HUMAN (195-605): 1.31e-84: 275: 15.79		PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42
+	Hs
		269826 FBXW7_HUMAN (4-601): 3.88e-73: 251: 12.71		PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42
+	Hs
		585518 FBXW7_HUMAN (4-601): 3.88e-73: 251: 12.71		E2AK2_HUMAN (98-258): 1.74e-11: 68.9: 22.67
+	Hs
		269670 WDR5_HUMAN (135-467): 5.01e-40: 151: 11.18		PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42
+	Hs
		903179 WDR5_HUMAN (135-467): 5.01e-40: 151: 11.18		ILF3_HUMAN (245-488): 2.36e-15: 81.6: 15.45