Interactor 1: DC1I1 (O14576)
Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1)
Gene: DYNC1I1

Interactor 2: DC1I2 (Q13409)
Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)
Gene: DYNC1I2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.900

The method score is based on:

Property Details
Experiments 28718761, 36652389, 28514442, 33961781
Identification Methods affinity chromatography technology, cross-linking study, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Dynein_IC2~Dynein_IC2, WD40~WD40
Common GO terms GO:0003777 - microtubule motor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005868 - cytoplasmic dynein complex
GO:0005874 - microtubule
and 4 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 645
Hs

1 638
+ Hs
+ Hs
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+ Cr
+ Cr
+ Hs
+ Dm
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+ Hs
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+ Ce
+ Hs

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Last updated: 15 Jul 2024