Protein: UBX
Homeotic protein ultrabithorax

Gene: UBX
Organism: Drosophila melanogaster
Interactions: 233
UniProt ID: P83949

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0001221 - transcription coregulator binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

823995

EXD
Homeobox protein extradenticle

7

20

Small-scale

0.966

High

1014305

AL
Homeobox protein aristaless

3

20

Small-scale

0.876

High

652142

TIN
Muscle-specific homeobox protein tinman

3

20

Small-scale

0.845

High

569353

HAIR
Protein hairy

1

6

Small-scale

0.766

High

444064

EVE
Segmentation protein even-skipped

2

20

High-throughput

0.754

High

528895

TWIST
Protein twist

2

20

High-throughput

0.754

High

614870

EMS
Homeotic protein empty spiracles

2

20

High-throughput

0.754

High

627199

DLL
Homeotic protein distal-less

2

20

High-throughput

0.754

High

652947

SLOU
Homeobox protein slou

2

19

High-throughput

0.754

High

652991

BAGP
Homeobox protein bagpipe

2

19

High-throughput

0.754

High

653115

MYOD
Myogenic-determination protein

2

16

High-throughput

0.754

High

714741

APTE
Protein apterous

2

20

High-throughput

0.754

High

827984

MEF2
Myocyte-specific enhancer factor 2

2

3

High-throughput

0.754

High

1014383

Q9VJ37
Insulin gene enhancer protein ISL-1

2

18

High-throughput

0.754

High

1014395

Q9VMR2
LP04777p

2

20

High-throughput

0.754

High

1014405

Q9VST2
Dorsocross2

2

20

High-throughput

0.754

High

1014340

Q8MLR4
Regulatory protein zeste

4

3

Small-scale

0.685

High

900613

DSH
Segment polarity protein dishevelled

2

5

Small-scale

0.637

High

1014315

NOC
Zinc finger protein Noc

2

8

Small-scale

0.637

High

355854

O96660
Mothers against decapentaplegic homolog

2

17

Small-scale

0.633

High

1014341

Q8MRC7
DISCO interacting protein 1, isoform E

2

2

Small-scale

0.633

High

1014362

Q9V406
Activator protein 4

1

0

Small-scale

0.631

High

84294

DIMM
Protein dimmed

1

16

High-throughput

0.621

High

84569

B7YZU0
Pou domain motif 3, isoform C

1

20

High-throughput

0.621

High

194885

ARNT
Aryl hydrocarbon receptor nuclear translocator homolog

1

12

High-throughput

0.621

High

197571

PAX6
Paired box protein Pax-6

1

20

High-throughput

0.621

High

197685

PITX
Pituitary homeobox homolog Ptx1

1

20

High-throughput

0.621

High

235202

HTH
Homeobox protein homothorax

1

20

High-throughput

0.621

High

305088

UNC4
Homeobox protein unc-4

1

20

High-throughput

0.621

High

393634

ANTP
Homeotic protein antennapedia

1

20

High-throughput

0.621

High

393663

FTZ
Segmentation protein fushi tarazu

1

19

High-throughput

0.621

High

458220

DFD
Homeotic protein deformed

1

20

High-throughput

0.621

High

478792

BCD
Homeotic protein bicoid

1

20

High-throughput

0.621

High

478865

GSBN
Protein gooseberry-neuro

1

20

High-throughput

0.621

High

478944

ABDB
Homeobox protein abdominal-B

1

19

High-throughput

0.621

High

542907

DA
Protein daughterless

1

1

High-throughput

0.621

High

593557

CF1A
POU domain protein CF1A

1

20

High-throughput

0.621

High

614987

EMC
Protein extra-macrochaetae

1

3

High-throughput

0.621

High

652966

VND
Homeobox protein vnd

1

20

High-throughput

0.621

High

701341

ZFH1
Zinc finger protein 1

1

17

High-throughput

0.621

High

713661

ABDA
Homeobox protein abdominal-A

1

19

Small-scale

0.621

High

1014298

ESMC
Enhancer of split mgamma protein

1

6

High-throughput

0.621

High

1014299

ESMD
Enhancer of split mdelta protein

1

6

High-throughput

0.621

High

1014303

BSH
Brain-specific homeobox protein

1

20

High-throughput

0.621

High

1014307

Q0IGU7
HLH54F

1

16

High-throughput

0.621

High

1014316

SRF
Serum response factor homolog

1

1

High-throughput

0.621

High

1014317

SO
Protein sine oculis

1

20

High-throughput

0.621

High

1014324

Q7JR08
Achintya, isoform A

1

20

High-throughput

0.621

High

1014329

HEY
Hairy/enhancer-of-split related with YRPW motif protein

1

10

High-throughput

0.621

High

1014331

Q7KS72
C15

1

20

High-throughput

0.621

High

1014347

OPTIX
Protein Optix

1

20

High-throughput

0.621

High

1014358

Q9U8L5
Dorsocross1, isoform A

1

20

High-throughput

0.621

High

1014369

Q9VDF0
Hematopoietically expressed homeobox

1

20

High-throughput

0.621

High

1014376

Q9VFK4
NK7.1, isoform A

1

20

High-throughput

0.621

High

1014389

Q9VL05
FI14601p

1

18

High-throughput

0.621

High

1014404

Q9VSC2
Extra-extra

1

19

High-throughput

0.621

High

1014417

Q9W1H7
Putative homeodomain protein

1

20

High-throughput

0.621

High

1014422

Q9W3F4
Optomotor-blind-related-gene-1, isoform A

1

20

High-throughput

0.621

High

1014423

Q9W423
LD18904p

1

4

High-throughput

0.621

High

1014427

Q9XZU0
FI01102p

1

20

High-throughput

0.621

High

1014428

AMOS
Basic helix-loop-helix transcription factor amos

1

14

High-throughput

0.621

High

1014429

Q9Y1P6
GM13131p

1

20

High-throughput

0.621

High

1014430

X2JDS9
Visual system homeobox 2

1

20

High-throughput

0.621

High

616516

ARM
Armadillo segment polarity protein

2

0

Small-scale

0.618

High

1014327

NCBP1
Nuclear cap-binding protein subunit 1

2

0

Small-scale

0.618

High

1014297

1433E
14-3-3 protein epsilon

2

0

Small-scale

0.610

High

95181

E1JIC9
Transcription initiation factor IIE subunit beta

2

4

Small-scale

0.609

High

234462

CTBP
C-terminal-binding protein

2

6

Small-scale

0.606

High

559130

ELF1
Protein grainyhead

2

1

Small-scale

0.606

High

1014361

Q9V3W9
UV excision repair protein RAD23

1

2

Small-scale

0.594

High

1014354

Q9TW27
DISCO interacting protein 1, isoform D

1

2

Small-scale

0.586

High

1014379

Q9VHM3
LD30467p

2

19

Small-scale

0.584

High

532119

KNIR
Zygotic gap protein knirps

2

20

High-throughput

0.584

High

646988

TSH
Protein teashirt

2

5

High-throughput

0.584

High

701278

SUH
Suppressor of hairless protein

2

9

High-throughput

0.584

High

732010

SLP2
Fork head domain transcription factor slp2

2

20

High-throughput

0.584

High

837131

MAD
Protein mothers against dpp

2

17

High-throughput

0.584

High

1014333

Q7PLI0
Adherens junction protein p120

2

3

Small-scale

0.584

High

1014402

FOXF
Forkhead box protein biniou

2

20

High-throughput

0.584

High

356741

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

6

Small-scale

0.581

High

538230

HSP7D
Heat shock 70 kDa protein cognate 4

1

3

Small-scale

0.581

High

1014350

Q961D1
Cyclin-K

1

4

Small-scale

0.573

High

543366

TERM
Protein terminus

2

0

High-throughput

0.570

High

1014409

MED19
Mediator of RNA polymerase II transcription subunit 19

2

4

Small-scale

0.566

High

1014353

EF1G
Elongation factor 1-gamma

1

0

Small-scale

0.557

High

898321

RL22
Large ribosomal subunit protein eL22

2

1

Small-scale

0.556

High

1014343

Q8T030
Mitogen-activated protein kinase

1

8

Small-scale

0.552

High

1014328

PSD11
26S proteasome non-ATPase regulatory subunit 11

2

2

Small-scale

0.543

High

521163

OTU
Deubiquitinase otu

1

2

Small-scale

0.531

High

356154

O96881
Transcription initiation factor IIE subunit beta

1

4

Small-scale

0.526

High

1014355

Q9TZQ2
Mothers against decapentaplegic homolog

1

17

Small-scale

0.526

High

68264

A8DYD3
Combgap, isoform F

1

4

Small-scale

0.515

High

355758

O96378
RE17884p

1

1

Small-scale

0.515

High

674012

BRM
ATP-dependent helicase brm

1

7

Small-scale

0.515

High

1014304

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

1

Small-scale

0.515

High

1014338

Q8IMV6
Scaffold attachment factor B, isoform B

1

2

Small-scale

0.515

High

1014390

Q9VL71
LD29830p

1

4

Small-scale

0.515

High

1014359

Q9V3E7
LD24793p

1

1

Small-scale

0.508

High

1014308

Q23993
Mitogen-activated protein kinase

1

9

Small-scale

0.501

High

602157

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

Small-scale

0.493

High

814160

BX42
Puff-specific protein Bx42

1

0

Small-scale

0.493

High

1014360

Q9V3W7
LD40489p

1

0

Small-scale

0.493

High

1014374

Q9VEJ1
Branchpoint-bridging protein

1

0

Small-scale

0.493

High

1014396

Q9VNC1
Large ribosomal subunit protein mL44

1

0

High-throughput

0.486

High

559796

EF2
Eukaryotic translation elongation factor 2

1

1

Small-scale

0.481

High

54196

A1Z8A4
Pipsqueak, isoform A

1

20

High-throughput

0.481

High

55223

A1Z995
Sequoia, isoform A

1

3

High-throughput

0.481

High

120234

M9PCZ7
SoxNeuro, isoform B

1

20

High-throughput

0.481

High

120525

M9PD94
Crooked legs, isoform F

1

4

High-throughput

0.481

High

121513

M9PFG6
Sox21a, isoform B

1

20

High-throughput

0.481

High

304841

E2F2
Transcription factor E2F2

1

5

High-throughput

0.481

High

405639

MYB
Myb protein

1

1

High-throughput

0.481

High

423568

HUNB
Protein hunchback

1

13

High-throughput

0.481

High

426652

HP1
Heterochromatin protein 1

1

6

High-throughput

0.481

High

458821

SRYB
Serendipity locus protein beta

1

11

High-throughput

0.481

High

488676

ZEST
Regulatory protein zeste

1

1

High-throughput

0.481

High

561775

MODU
DNA-binding protein modulo

1

1

High-throughput

0.481

High

583774

EGON
Protein embryonic gonad

1

20

High-throughput

0.481

High

594680

GROU
Protein groucho

1

20

High-throughput

0.481

High

594741

7UP1
Steroid receptor seven-up, isoforms B/C

1

14

High-throughput

0.481

High

613684

JRA
Transcription factor Jra

1

17

High-throughput

0.481

High

638755

FOSLA
Transcription factor kayak, isoforms A/B/F

1

18

High-throughput

0.481

High

643292

CPD1
Chromosomal protein D1

1

1

High-throughput

0.481

High

653079

HSF
Heat shock factor protein

1

1

High-throughput

0.481

High

662105

POXM
Paired box pox-meso protein

1

20

High-throughput

0.481

High

662915

ODD
Protein odd-skipped

1

15

High-throughput

0.481

High

683145

ESCA
Protein escargot

1

16

High-throughput

0.481

High

706393

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.481

High

717018

SCAL
Protein scalloped

1

4

High-throughput

0.481

High

726296

HR3
Probable nuclear hormone receptor HR3

1

12

High-throughput

0.481

High

731996

FD5
Fork head domain-containing protein FD5

1

20

High-throughput

0.481

High

812990

GIANT
Protein giant

1

5

High-throughput

0.481

High

814650

PHP
Polyhomeotic-proximal chromatin protein

1

20

High-throughput

0.481

High

831904

PEP
Zinc finger protein on ecdysone puffs

1

1

High-throughput

0.481

High

892162

HNF4
Transcription factor HNF-4 homolog

1

13

High-throughput

0.481

High

903021

OVO
Transcriptional regulator ovo

1

12

High-throughput

0.481

High

909934

PNR
GATA-binding factor A

1

14

High-throughput

0.481

High

909943

SRP
Box A-binding factor

1

14

High-throughput

0.481

High

942212

COLL
Transcription factor collier

1

3

High-throughput

0.481

High

1014300

CEBP
CCAAT/enhancer-binding protein

1

11

High-throughput

0.481

High

1014302

ELG
DNA-binding protein Ets97D

1

16

High-throughput

0.481

High

1014306

GAGA
Transcription activator GAGA

1

20

High-throughput

0.481

High

1014310

HR78
Nuclear hormone receptor HR78

1

20

High-throughput

0.481

High

1014311

HR96
Nuclear hormone receptor HR96

1

20

High-throughput

0.481

High

1014312

ABRU
Protein abrupt

1

17

High-throughput

0.481

High

1014313

DEAF1
Deformed epidermal autoregulatory factor 1

1

8

High-throughput

0.481

High

1014314

ESC
Polycomb protein esc

1

6

High-throughput

0.481

High

1014318

Q4QPP9
GH02096p

1

16

High-throughput

0.481

High

1014319

RCOR
REST corepressor

1

9

High-throughput

0.481

High

1014321

Q5BIC3
Az2

1

16

High-throughput

0.481

High

1014322

Q7JN06
Boundary element associated factor

1

1

High-throughput

0.481

High

1014323

Q7JQY8
LD40262p

1

6

High-throughput

0.481

High

1014332

CAS
Transcription factor castor

1

9

High-throughput

0.481

High

1014335

Q86BR8
Mitochondrial transcription factor A, isoform B

1

20

High-throughput

0.481

High

1014336

TULP
Protein king tubby

1

1

High-throughput

0.481

High

1014337

PANG2
Protein pangolin, isoform J

1

20

High-throughput

0.481

High

1014344

HDAC1
Histone deacetylase HDAC1

1

6

High-throughput

0.481

High

1014345

ASH2
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

4

High-throughput

0.481

High

1014346

Q94883
DNA replication-related element factor, isoform A

1

1

High-throughput

0.481

High

1014348

FOXO
Forkhead box protein O

1

20

High-throughput

0.481

High

1014349

TIP60
Histone acetyltransferase Tip60

1

5

High-throughput

0.481

High

1014351

Q9N6D8
GH11591p

1

3

High-throughput

0.481

High

1014356

TIPT
Protein tiptop

1

5

High-throughput

0.481

High

1014357

GRAU
Transcription factor grauzone

1

11

High-throughput

0.481

High

1014365

CHRC
Chromatin accessibility complex 16kD protein

1

1

High-throughput

0.481

High

1014366

Q9V481
Forkhead domain 102C

1

20

High-throughput

0.481

High

1014367

ZIPIC
Zinc finger protein ZIPIC

1

12

High-throughput

0.481

High

1014370

Q9VDF1
Doublesex-Mab related 93B

1

5

High-throughput

0.481

High

1014371

Q9VDQ4
Trade embargo

1

10

High-throughput

0.481

High

1014372

SQZ
Zinc finger protein squeeze

1

10

High-throughput

0.481

High

1014373

Q9VEF0
LD33778p

1

20

High-throughput

0.481

High

1014375

Q9VF03
Brahma associated protein 155 kDa

1

5

High-throughput

0.481

High

1014377

Q9VFX8
FI14740p

1

1

High-throughput

0.481

High

1014380

Q9VI12
Hormone receptor 83

1

19

High-throughput

0.481

High

1014381

Q9VI24
LD25151p

1

20

High-throughput

0.481

High

1014382

RN
Zinc finger protein rotund

1

10

High-throughput

0.481

High

1014384

WEK
Zinc finger protein weckle

1

13

High-throughput

0.481

High

1014386

NC2B
Protein Dr1

1

5

High-throughput

0.481

High

1014387

Q9VKC4
FI01124p

1

10

High-throughput

0.481

High

1014391

Q9VL91
LD23102p

1

5

Small-scale

0.481

High

1014392

TCP4
RNA polymerase II transcriptional coactivator

1

1

High-throughput

0.481

High

1014393

Q9VM61
Uncharacterized protein, isoform A

1

6

High-throughput

0.481

High

1014394

KDM5
Lysine-specific demethylase 5

1

9

High-throughput

0.481

High

1014397

Q9VP57
LD15904p

1

8

High-throughput

0.481

High

1014399

DRM
Protein drumstick

1

18

High-throughput

0.481

High

1014400

Q9VRV4
D19B

1

7

High-throughput

0.481

High

1014403

Q9VS55
CTCF

1

7

High-throughput

0.481

High

1014406

Q9VTD3
FI01015p

1

10

High-throughput

0.481

High

1014407

Q9VUD3
GH07353p

1

20

High-throughput

0.481

High

1014412

CREBB
Cyclic AMP response element-binding protein B

1

6

High-throughput

0.481

High

1014415

BAB1
Protein bric-a-brac 1

1

13

High-throughput

0.481

High

1014418

Q9W2F0
LD45439p

1

15

High-throughput

0.481

High

1014420

Q9W2K8
High mobility group protein 2

1

20

High-throughput

0.481

High

1014421

Q9W396
FI06908p

1

6

High-throughput

0.481

High

1014424

Q9W4Q1
Forkhead domain 3F, isoform C

1

20

High-throughput

0.481

High

1014425

Q9W5E6
Histone H4 transcription factor, isoform C

1

11

High-throughput

0.481

High

683566

YEMA
yemanuclein

1

0

Small-scale

0.480

High

1014342

PHO
Polycomb protein PHO

1

16

Small-scale

0.479

High

1014416

Q9W137
LD29879p

1

10

High-throughput

0.479

High

1014330

Q7KM15
Transcription factor BTF3

1

1

Small-scale

0.470

High

1014398

Q9VQF5
Cwc25

1

1

Small-scale

0.470

High

661886

NRT
Neurotactin

1

3

Small-scale

0.464

High

1014309

BRO
Protein brother

1

0

High-throughput

0.460

High

1014326

Q7K3Q3
Regulatory protein zeste

1

0

High-throughput

0.460

High

1014378

Q9VHL0
Hinge2

1

0

High-throughput

0.460

High

1014388

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

0

High-throughput

0.460

High

1014401

Q9VRV8
Transportin-1

1

0

Small-scale

0.460

High

1014414

ECD
Protein ecdysoneless

1

0

High-throughput

0.460

High

1014419

Q9W2K3
CG9437 protein

1

0

High-throughput

0.460

High

231905

O44122
Zinc finger 30C

1

5

Small-scale

0.457

High

1014352

Q9NHP1
Arm repeat protein

1

3

Small-scale

0.457

High

55994

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

1

1

High-throughput

0.439

High

98442

F0JAG2
MIP27703p

1

1

Small-scale

0.439

High

391887

HSP83
Heat shock protein 83

1

1

High-throughput

0.439

High

1014325

Q7K3G5
D4, isoform A

1

18

High-throughput

0.439

High

1014339

Q8IN74
FI10013p

1

1

High-throughput

0.439

High

1014364

DPOE3
DNA polymerase epsilon subunit 3

1

5

High-throughput

0.439

High

1014368

Q9VB35
Sidestep, isoform A

1

1

High-throughput

0.439

High

1014385

Q9VJP8
RE16347p

1

1

High-throughput

0.439

High

871605

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

1

2

High-throughput

0.437

High

1014334

Q86BI3
Zinc-finger protein at 72D, isoform B

1

3

Small-scale

0.417

High

1014363

Q9V435
Yuri gagarin, isoform B

1

1

High-throughput

0.417

High

1014411

S6KL
Serine/threonine-protein kinase S6KL

1

7

High-throughput

0.417

High

1014301

RS13
Small ribosomal subunit protein uS15

1

0

Small-scale

0.303

High

198003

FZO
Transmembrane GTPase fzo

1

0

High-throughput

0.265

Low

1014296

MIC60
MICOS complex subunit Mic60

1

0

Small-scale

0.265

Low

1014408

Q9VUG5
GEO02333p1

1

0

High-throughput

0.265

Low

1014410

Q9VW23
Male sterile

1

0

High-throughput

0.265

Low

1014413

Q9VYA4
Ribonuclease H2 subunit B

1

0

High-throughput

0.265

Low

195585

O16528
Bearded

1

0

Small-scale

0.261

Low

1014426

PYG
Glycogen phosphorylase

1

0

Small-scale

0.251

Low

120531

M9PDA5
Uncharacterized protein, isoform B

1

0

High-throughput

0.249

Low

1014320

Q59E43
Uncharacterized protein, isoform B

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025