HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: CENPF (P49454)
Centromere protein F (CENP-F) (AH antigen) (Kinetochore protein CENPF) (Mitosin)
Gene: CENPF

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000278 - mitotic cell cycle GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2027 Hs			1 3114
+	Hs
		148769 CTRO_HUMAN (1-2027): 0: 1212: 100.00		GOGA4_HUMAN (1445-3105): 1.51e-54: 214: 11.34
+	Hs
		148460 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH9_HUMAN (2390-3109): 2.8e-24: 115: 11.50
+	Hs
		148126 CTRO_HUMAN (1-2027): 0: 1212: 100.00		CTRO_HUMAN (9-523): 1.93e-13: 79.3: 16.06
+	Hs
		148466 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH11_HUMAN (1-426): 4.11e-13: 78.1: 16.82
+	Hs
		148359 CTRO_HUMAN (1-2027): 0: 1212: 100.00		DESP_HUMAN (282-945): 7.09e-11: 70.9: 19.30
+	Hs
		148461 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH10_HUMAN (2766-3108): 1.96e-09: 66.2: 11.59
+	Hs
		149126 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MY18A_HUMAN (1979-2555): 3.75e-09: 65.1: 18.84
+	Hs
		149218 CTRO_HUMAN (1-2027): 0: 1212: 100.00		AKAP9_HUMAN (1-509): 3.84e-09: 65.1: 11.22
+	Hs
		116964 SGK1_HUMAN (59-407): 8.42e-121: 390: 31.37		MYH1_HUMAN (2522-3083): 1.13e-14: 83.1: 12.68
+	Mm
		1130947 AKT2_MOUSE (44-403): 7.42e-122: 395: 31.20		GRDN_MOUSE (1801-2855): 3.23e-12: 75.1: 21.44
+	Hs
		725079 ST38L_HUMAN (74-430): 6.61e-69: 242: 35.79		MYH9_HUMAN (2390-3109): 2.8e-24: 115: 11.50
+	Hs
		149340 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		CTRO_HUMAN (9-523): 1.93e-13: 79.3: 16.06
+	Hs
		1344953 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		DAPLE_HUMAN (299-1163): 5.64e-09: 64.7: 21.44
+	Rn
		92843 ROCK2_RAT (864-1552): 1.94e-37: 156: 12.16		CTRO_RAT (9-523): 3.56e-11: 71.9: 17.12
+	Rn
		222476 MRCKA_RAT (536-1070): 1.62e-33: 144: 11.97		MRCKB_RAT (2279-2809): 1.17e-11: 73.2: 22.42
+	Hs
		724810 ROCK1_HUMAN (1051-1566): 8.4e-21: 102: 10.08		MYH9_HUMAN (2390-3109): 2.8e-24: 115: 11.50
+	Rn
		1186812 MRCKB_RAT (566-1070): 2.51e-33: 143: 12.74		MRCKB_RAT (2279-2809): 1.17e-11: 73.2: 22.42
+	Hs
		1137917 MRCKA_HUMAN (536-1061): 4.38e-32: 139: 11.82		MRCKB_HUMAN (2279-2818): 8.77e-11: 70.5: 21.73
+	Hs
		1268126 MRCKB_HUMAN (569-1070): 4.13e-33: 143: 12.04		MY18A_HUMAN (1979-2555): 3.75e-09: 65.1: 18.84
+	Hs
		254476 ROCK1_HUMAN (1051-1566): 8.4e-21: 102: 10.08		ROCK2_HUMAN (2147-2888): 4.08e-09: 64.7: 19.39