HitPredict

Interactor 1: TPPC4 (Q9Y296)
Trafficking protein particle complex subunit 4 (Hematopoietic stem/progenitor cell protein 172) (Synbindin) (TRS23 homolog)
Gene: TRAPPC4

Interactor 2: TPPC1 (Q9Y5R8)
Trafficking protein particle complex subunit 1 (BET5 homolog) (Multiple myeloma protein 2) (MUM-2)
Gene: TRAPPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.927

The method score is based on:

Property	Details
Experiments	28514442, 27173435, 33961781, 35271311, 37071682
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Sybindin~Sybindin
Common GO terms	GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006901 - vesicle coating and 5 others more... GO:0030008 - TRAPP complex GO:0048208 - COPII vesicle coating GO:0099022 - vesicle tethering GO:1990071 - TRAPPII protein complex GO:1990072 - TRAPPIII protein complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	219
Hs

1	145

Service provided by Combinatics, Japan

Last updated: 11Aug2025