Protein: TPPC4
Trafficking protein particle complex subunit 4 (Hematopoietic stem/progenitor cell protein 172) (Synbindin) (TRS23 homolog)

Gene: TPPC4, TRAPPC4
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q9Y296

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005795 - Golgi stack
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1490636

TPPC1
Trafficking protein particle complex subunit 1

5

4

High-throughput

0.927

High

1153512

RAB30
Ras-related protein Rab-30

2

3

High-throughput

0.811

High

1307861

TPPC5
Trafficking protein particle complex subunit 5

2

5

High-throughput

0.811

High

221766

TPPC3
Trafficking protein particle complex subunit 3

2

8

High-throughput

0.754

High

1420174

B2L14
Apoptosis facilitator Bcl-2-like protein 14

4

1

High-throughput

0.699

High

1358532

TPC12
Trafficking protein particle complex subunit 12

4

1

Small-scale

0.695

High

967247

RRAS2
Ras-related protein R-Ras2

1

2

High-throughput

0.691

High

515745

TPC2B
Trafficking protein particle complex subunit 2B

4

8

Small-scale

0.677

High

1214247

KANK4
KN motif and ankyrin repeat domain-containing protein 4

3

1

High-throughput

0.662

High

1461403

TPC2L
Trafficking protein particle complex subunit 2-like protein

3

8

Small-scale

0.658

High

376113

RASK
GTPase KRas

1

0

High-throughput

0.656

High

593717

BGAL
Beta-galactosidase

2

1

High-throughput

0.628

High

1430842

STMN4
Stathmin-4

2

1

High-throughput

0.628

High

1454706

TBC14
TBC1 domain family member 14

2

1

High-throughput

0.628

High

1212067

TPC3L
Trafficking protein particle complex subunit 3-like protein

1

8

Small-scale

0.621

High

1490633

TPPC4
Trafficking protein particle complex subunit 4

1

3

Small-scale

0.621

High

1295426

RAB43
Ras-related protein Rab-43

1

3

High-throughput

0.618

High

1276049

TPC11
Trafficking protein particle complex subunit 11

2

3

Small-scale

0.614

High

1400880

RAB3I
Rab-3A-interacting protein

2

3

Small-scale

0.612

High

1396011

CABS1
Calcium-binding and spermatid-specific protein 1

3

1

High-throughput

0.609

High

662522

GATA2
Endothelial transcription factor GATA-2

2

0

High-throughput

0.602

High

1429770

BTBD1
BTB/POZ domain-containing protein 1

2

0

High-throughput

0.602

High

874071

TPC10
Trafficking protein particle complex subunit 10

2

4

Small-scale

0.586

High

1400447

TPPC9
Trafficking protein particle complex subunit 9

2

2

Small-scale

0.586

High

730367

1433B
14-3-3 protein beta/alpha

1

4

High-throughput

0.536

High

783180

ARL3
ADP-ribosylation factor-like protein 3

1

1

High-throughput

0.536

High

943631

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

1

High-throughput

0.536

High

1384776

ARL8A
ADP-ribosylation factor-like protein 8A

1

2

High-throughput

0.536

High

1387452

CMBL
Carboxymethylenebutenolidase homolog

1

1

High-throughput

0.536

High

1450644

ARL8B
ADP-ribosylation factor-like protein 8B

1

2

High-throughput

0.536

High

1462718

GAB2
GRB2-associated-binding protein 2

1

1

High-throughput

0.536

High

703750

MK01
Mitogen-activated protein kinase 1

1

2

Small-scale

0.529

High

1458252

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.518

High

212351

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

0

High-throughput

0.513

High

219770

KCNQ3
Potassium voltage-gated channel subfamily KQT member 3

1

0

High-throughput

0.513

High

958386

ARP2
Actin-related protein 2

1

0

High-throughput

0.513

High

1036703

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

0

High-throughput

0.513

High

1121996

ARHG7
Rho guanine nucleotide exchange factor 7

1

0

High-throughput

0.513

High

1228743

C102B
Coiled-coil domain-containing protein 102B

1

0

High-throughput

0.513

High

1413509

AASD1
Alanyl-tRNA editing protein Aarsd1

1

0

High-throughput

0.513

High

1414172

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

1414930

MTND
Acireductone dioxygenase

1

0

High-throughput

0.513

High

1429548

MIS12
Protein MIS12 homolog

1

0

High-throughput

0.513

High

1461527

INTU
Protein inturned

1

0

High-throughput

0.513

High

1490635

MTL5
Tesmin

1

0

High-throughput

0.513

High

1253038

RUFY4
RUN and FYVE domain-containing protein 4

1

1

High-throughput

0.489

High

1490634

TPPC8
Trafficking protein particle complex subunit 8

1

1

Small-scale

0.481

High

423487

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

541766

FGFR1
Fibroblast growth factor receptor 1

1

1

High-throughput

0.479

High

1276376

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.479

High

1349059

R3GEF
Guanine nucleotide exchange factor for Rab-3A

1

3

High-throughput

0.479

High

1447738

PDLI7
PDZ and LIM domain protein 7

1

1

High-throughput

0.479

High

316182

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

931917

EPHA5
Ephrin type-A receptor 5

1

0

High-throughput

0.458

High

1141064

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1256154

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

691880

MK03
Mitogen-activated protein kinase 3

1

2

Small-scale

0.457

High

515663

TPC2A
Trafficking protein particle complex subunit 2

1

8

High-throughput

0.445

High

1098772

NDK3
Nucleoside diphosphate kinase 3

1

1

High-throughput

0.445

High

218979

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

560561

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.437

High

1031608

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.437

High

1251983

LMTK1
Serine/threonine-protein kinase LMTK1

1

1

High-throughput

0.437

High

1314649

M21D2
Nucleotidyltransferase MB21D2

1

3

High-throughput

0.437

High

1331948

TM102
Transmembrane protein 102

1

3

High-throughput

0.437

High

1391871

AURKB
Aurora kinase B

1

0

High-throughput

0.426

High

1312851

CI040
Uncharacterized protein C9orf40

1

1

High-throughput

0.407

High

1186445

ASTRB
Protein Aster-B

2

0

High-throughput

0.328

High

1326709

PTGR3
Prostaglandin reductase 3

2

0

High-throughput

0.313

High

326273

PRS23
Serine protease 23

1

0

High-throughput

0.282

High

605030

HXB6
Homeobox protein Hox-B6

1

0

High-throughput

0.279

Low

1329713

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

0

High-throughput

0.279

Low

1387351

OTUB2
Ubiquitin thioesterase OTUB2

1

0

High-throughput

0.279

Low

1404159

CNN2
Calponin-2

1

0

High-throughput

0.279

Low

854599

S15A1
Solute carrier family 15 member 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025