HitPredict

Interactor 1: SUCB2 (Q9Z2I8)
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (G-SCS) (GTPSCS) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG)
Gene: Suclg2

Interactor 2: SUCB2 (Q9Z2I8)
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (G-SCS) (GTPSCS) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG)
Gene: Suclg2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

The method score is based on:

Property	Details
Experiments	29199018, 29222160
Identification Methods	cross-linking study
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	ATP-grasp_2~ATP-grasp_2, ATP-grasp_2~Ligase_CoA, Ligase_CoA~Ligase_CoA
Common GO terms	GO:0000287 - magnesium ion binding GO:0004775 - succinate-CoA ligase (ADP-forming) activity GO:0004776 - succinate-CoA ligase (GDP-forming) activity GO:0004777 - succinate-semialdehyde dehydrogenase (NAD+) activity GO:0005524 - ATP binding and 9 others more... GO:0005525 - GTP binding GO:0005739 - mitochondrion GO:0005886 - plasma membrane GO:0006099 - tricarboxylic acid cycle GO:0006104 - succinyl-CoA metabolic process GO:0006105 - succinate metabolic process GO:0019003 - GDP binding GO:0044877 - protein-containing complex binding GO:0045244 - succinate-CoA ligase complex (GDP-forming)
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	433
Mm

1	433

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Last updated: 11Aug2025