HitPredict

Interactor 1: RFXK (O14593)
DNA-binding protein RFXANK (Ankyrin repeat family A protein 1) (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein)
Gene: RFXANK

Interactor 2: HDAC9 (Q9UKV0)
Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR)
Gene: HDAC9

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	15964851
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042826 - histone deacetylase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 260 Hs			1 1011
+	Hs
		1334238 ANRA2_HUMAN (34-252): 1.29e-72: 226: 57.27		HDAC9_HUMAN (1-1011): 0: 799: 100.00
+	Hs
		149843 RFXK_HUMAN (1-260): 9.49e-85: 255: 100.00		HDAC4_HUMAN (1-1009): 0: 691: 54.67
+	Mm
		1157859 RFXK_MOUSE (1-260): 5.16e-76: 233: 81.11		HDAC4_MOUSE (1-1009): 0: 684: 53.86
+	Hs
		880823 ANRA2_HUMAN (34-252): 1.29e-72: 226: 57.27		HDAC4_HUMAN (1-1009): 0: 691: 54.67
+	Hs
		149938 RFXK_HUMAN (1-260): 9.49e-85: 255: 100.00		HDAC5_HUMAN (1-1008): 0: 612: 55.67
+	Mm
		1112794 RFXK_MOUSE (1-260): 5.16e-76: 233: 81.11		Q3UJF1_MOUSE (1-1008): 0: 609: 54.42
+	Hs
		1334240 ANRA2_HUMAN (34-252): 1.29e-72: 226: 57.27		HDAC5_HUMAN (1-1008): 0: 612: 55.67
+	Mm
		56845 TANC2_MOUSE (5-179): 6.54e-13: 70.4: 13.71		HDAC4_MOUSE (1-1009): 0: 684: 53.86
+	Mm
		1157667 TNKS1_MOUSE (2-77): 4.04e-12: 67.7: 11.84		HDAC4_MOUSE (1-1009): 0: 684: 53.86
+	Mm
		1112781 ANRA2_MOUSE (183-259): 2.06e-16: 78.9: 25.97		Q3UJF1_MOUSE (1-1008): 0: 609: 54.42
+	Hs
		149897 RFXK_HUMAN (1-260): 9.49e-85: 255: 100.00		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67
+	Hs
		177384 ANRA2_HUMAN (34-252): 1.29e-72: 226: 57.27		HDAC3_HUMAN (631-1007): 9.3e-131: 404: 22.34
+	Hs
		1038631 EHMT2_HUMAN (61-259): 7.74e-55: 191: 22.28		HDAC1_HUMAN (623-1009): 3.2e-140: 430: 23.49
+	Hs
		257609 ANR17_HUMAN (4-258): 3.71e-54: 189: 17.24		HDAC1_HUMAN (623-1009): 3.2e-140: 430: 23.49
+	Hs
		1270381 EHMT2_HUMAN (61-259): 7.74e-55: 191: 22.28		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67
+	Hs
		257678 ANR17_HUMAN (4-258): 3.71e-54: 189: 17.24		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67
+	Hs
		166921 ANR28_HUMAN (2-211): 3.9e-44: 160: 15.48		HDAC1_HUMAN (623-1009): 3.2e-140: 430: 23.49
+	Hs
		1038721 EHMT1_HUMAN (2-146): 1.31e-31: 124: 11.64		HDAC1_HUMAN (623-1009): 3.2e-140: 430: 23.49
+	Hs
		1270450 EHMT1_HUMAN (2-146): 1.31e-31: 124: 11.64		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67
+	Hs
		1219802 ANKH1_HUMAN (2-123): 4.24e-29: 117: 13.82		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67