HitPredict

Interactor 1: CTDS2 (O14595)
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 2) (NLI-interacting factor 2) (Protein OS-4) (Small C-terminal domain phosphatase 2) (Small CTD phosphatase 2) (SCP2)
Gene: CTDSP2

Interactor 2: NEK4 (P51957)
Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (Never in mitosis A-related kinase 4) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2)
Gene: NEK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 271 Hs			1 841
+	Hs
		851523 TIM50_HUMAN (47-268): 7.15e-72: 226: 23.01		NEK4_HUMAN (1-841): 0: 617: 100.00
+	Hs
		149970 CTDS2_HUMAN (1-271): 3.69e-108: 315: 100.00		AKT1_HUMAN (1-330): 8.38e-132: 403: 23.44
+	Hs
		985673 CTSL2_HUMAN (54-266): 2.76e-74: 235: 36.82		MRCKA_HUMAN (3-780): 2.99e-129: 426: 19.17
+	At
		1105343 Q8VY28_ARATH (19-267): 1.38e-77: 243: 32.00		KIN10_ARATH (5-399): 1.79e-134: 411: 21.66
+	Hs
		1114383 TIM50_HUMAN (47-268): 7.15e-72: 226: 23.01		KS6B2_HUMAN (6-405): 5.48e-130: 399: 21.79
+	Hs
		682091 CTDP1_HUMAN (3-240): 2.1e-62: 213: 16.53		AKT1_HUMAN (1-330): 8.38e-132: 403: 23.44
+	At
		187509 Q8VY28_ARATH (19-267): 1.38e-77: 243: 32.00		CIPKB_ARATH (3-314): 7.3e-117: 363: 26.71
+	Hs
		150000 CTDS2_HUMAN (1-271): 3.69e-108: 315: 100.00		NEK1_HUMAN (3-269): 5.25e-78: 277: 50.56