HitPredict

Interactor 1: GBGT2 (O14610)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 (G gamma-C) (G-gamma-8) (G-gamma-9) (Guanine nucleotide binding protein gamma transducing activity polypeptide 2)
Gene: GNGT2

Interactor 2: GBB3 (P16520)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (Transducin beta chain 3)
Gene: GNB3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19168127
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	G-gamma~WD40
Common GO terms	GO:0003924 - GTPase activity GO:0005834 - heterotrimeric G-protein complex GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 69 Hs			1 340
+	Hs
		229235 GBG7_HUMAN (5-68): 5.07e-25: 89.3: 40.63		GBB3_HUMAN (1-340): 9.93e-106: 314: 100.00
+	Hs
		560868 GBG2_HUMAN (2-64): 1.98e-24: 88.2: 38.10		GBB3_HUMAN (1-340): 9.93e-106: 314: 100.00
+	Hs
		560893 GBG12_HUMAN (4-68): 3.85e-24: 87.4: 38.46		GBB3_HUMAN (1-340): 9.93e-106: 314: 100.00
+	Hs
		560872 GBG3_HUMAN (3-64): 4.75e-24: 87: 35.48		GBB3_HUMAN (1-340): 9.93e-106: 314: 100.00
+	Hs
		229238 GBG7_HUMAN (5-68): 5.07e-25: 89.3: 40.63		GBB2_HUMAN (1-340): 2.98e-103: 308: 78.49
+	Hs
		887097 GBG2_HUMAN (2-64): 1.98e-24: 88.2: 38.10		GBB2_HUMAN (1-340): 2.98e-103: 308: 78.49
+	Hs
		921761 GBG12_HUMAN (4-68): 3.85e-24: 87.4: 38.46		GBB2_HUMAN (1-340): 2.98e-103: 308: 78.49
+	Hs
		229245 GBG7_HUMAN (5-68): 5.07e-25: 89.3: 40.63		GBB4_HUMAN (1-340): 1.64e-102: 306: 77.33
+	Hs
		887126 GBG2_HUMAN (2-64): 1.98e-24: 88.2: 38.10		GBB4_HUMAN (1-340): 1.64e-102: 306: 77.33
+	Hs
		1334920 GBG12_HUMAN (4-68): 3.85e-24: 87.4: 38.46		GBB4_HUMAN (1-340): 1.64e-102: 306: 77.33
+	Hs
		229237 GBG7_HUMAN (5-68): 5.07e-25: 89.3: 40.63		GBB1_HUMAN (1-340): 2.78e-101: 303: 83.24
+	Hs
		887096 GBG2_HUMAN (2-64): 1.98e-24: 88.2: 38.10		GBB1_HUMAN (1-340): 2.78e-101: 303: 83.24
+	Bt
		920925 GBG2_BOVIN (2-64): 1.98e-24: 88.2: 38.10		GBB1_BOVIN (1-340): 2.78e-101: 303: 83.24
+	Mm
		921088 GBG2_MOUSE (2-64): 1.98e-24: 88.2: 38.10		GBB1_MOUSE (1-340): 2.78e-101: 303: 83.24
+	Hs
		921073 GBG12_HUMAN (4-68): 3.85e-24: 87.4: 38.46		GBB1_HUMAN (1-340): 2.78e-101: 303: 83.24
+	Hs
		920932 GBG3_HUMAN (3-64): 4.75e-24: 87: 35.48		GBB1_HUMAN (1-340): 2.78e-101: 303: 83.24
+	Hs
		154646 GBG7_HUMAN (5-68): 5.07e-25: 89.3: 40.63		GNB5_HUMAN (129-340): 2.4e-45: 160: 21.92
+	Hs
		154670 GBG2_HUMAN (2-64): 1.98e-24: 88.2: 38.10		GNB5_HUMAN (129-340): 2.4e-45: 160: 21.92
+	Hs
		154672 GBG3_HUMAN (3-64): 4.75e-24: 87: 35.48		GNB5_HUMAN (129-340): 2.4e-45: 160: 21.92
+	Hs
		887100 GBG2_HUMAN (2-64): 1.98e-24: 88.2: 38.10		RACK1_HUMAN (97-340): 4.64e-11: 64.7: 27.38