HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: DVL3 (Q92997)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.922

The method score is based on:

Property Details
Experiments 28514442, 33961781, 31340145, 36398662, 24643799
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEP~DEP, DIX~DIX, PDZ~PDZ
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005109 - frizzled binding
GO:0005829 - cytosol
GO:0031267 - small GTPase binding
GO:0032956 - regulation of actin cytoskeleton organization
and 8 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 736
Hs

1 716
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Last updated: 15 Jul 2024