HitPredict

Interactor 1: CHD1 (O14646)
Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1)
Gene: CHD1

Interactor 2: PHIP (Q8WWQ0)
PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
Gene: PHIP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29089422
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1710 Hs			1 1821
+	Hs
		1255033 CHD5_HUMAN (131-1386): 0: 861: 26.76		PHIP_HUMAN (1-1821): 0: 1502: 100.00
+	Hs
		1059760 CHD4_HUMAN (84-1512): 0: 839: 24.61		PHIP_HUMAN (1-1821): 0: 1502: 100.00
+	Hs
		151440 CHD1_HUMAN (1-1710): 0: 1217: 100.00		FBXW7_HUMAN (294-657): 3.51e-56: 211: 17.33
+	Dm
		332801 CHDM_DROME (23-1509): 0: 813: 24.02		Q8SX63_DROME (497-1685): 0: 608: 32.81
+	Hs
		151443 CHD1_HUMAN (1-1710): 0: 1217: 100.00		SNR40_HUMAN (355-666): 5.05e-55: 198: 13.23
+	Hs
		1016272 CHD3_HUMAN (32-1512): 0: 913: 25.34		TBL3_HUMAN (7-495): 2.68e-90: 315: 14.31
+	Hs
		1016277 CHD4_HUMAN (84-1512): 0: 839: 24.61		TBL3_HUMAN (7-495): 2.68e-90: 315: 14.31
+	Hs
		1018633 CHD3_HUMAN (32-1512): 0: 913: 25.34		SNR40_HUMAN (355-666): 5.05e-55: 198: 13.23
+	Hs
		903535 CHD8_HUMAN (30-1354): 0: 871: 25.62		WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62
+	Hs
		1018557 CHD3_HUMAN (32-1512): 0: 913: 25.34		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		903234 CHD4_HUMAN (84-1512): 0: 839: 24.61		WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62
+	Hs
		1059779 CHD4_HUMAN (84-1512): 0: 839: 24.61		FBXW7_HUMAN (294-657): 3.51e-56: 211: 17.33
+	Hs
		1199201 CHD8_HUMAN (30-1354): 0: 871: 25.62		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		1309165 CHD8_HUMAN (30-1354): 0: 871: 25.62		TBL1Y_HUMAN (306-597): 6.5e-41: 161: 15.69
+	Hs
		1059704 CHD4_HUMAN (84-1512): 0: 839: 24.61		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		197011 CHD3_HUMAN (32-1512): 0: 913: 25.34		PRP4_HUMAN (160-494): 2.06e-16: 86.7: 25.35
+	Hs
		1018714 CHD3_HUMAN (32-1512): 0: 913: 25.34		NLE1_HUMAN (1-79): 1.4e-13: 77.6: 12.66
+	Hs
		197020 CHD4_HUMAN (84-1512): 0: 839: 24.61		PRP4_HUMAN (160-494): 2.06e-16: 86.7: 25.35
+	Sc
		697375 CHD1_YEAST (256-1506): 0: 772: 34.54		BDF1_YEAST (1262-1490): 1.35e-23: 110: 20.78
+	Sc
		697383 CHD1_YEAST (256-1506): 0: 772: 34.54		TAF5_YEAST (181-311): 6.96e-09: 63.2: 32.58