HitPredict

Interactor 1: CHD2 (O14647)
Chromodomain-helicase-DNA-binding protein 2 (CHD-2) (EC 3.6.4.12) (ATP-dependent helicase CHD2)
Gene: CHD2

Interactor 2: H2BFS (P57053)
Histone H2B type F-S (H2B-clustered histone 12 like) (H2B.S histone 1) (Histone H2B.s) (H2B/s)
Gene: H2BC12L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1828 Hs			1 126
+	Hs
		151395 CHD1_HUMAN (82-1828): 0: 1027: 55.12		H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62
+	Hs
		1018625 CHD3_HUMAN (32-1580): 0: 981: 24.29		H2B1H_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		241517 CHD3_HUMAN (32-1580): 0: 981: 24.29		H2B1K_HUMAN (1-126): 7.6e-54: 166: 98.41
+	Hs
		707612 CHD3_HUMAN (32-1580): 0: 981: 24.29		H2B1B_HUMAN (1-126): 1.07e-53: 166: 95.24
+	Hs
		918325 CHD3_HUMAN (32-1580): 0: 981: 24.29		H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62
+	Hs
		1059648 CHD4_HUMAN (48-1562): 0: 967: 25.57		H2B2E_HUMAN (1-126): 3.9e-54: 167: 96.83
+	Hs
		1059777 CHD4_HUMAN (48-1562): 0: 967: 25.57		H2B1H_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		241527 CHD4_HUMAN (48-1562): 0: 967: 25.57		H2B1K_HUMAN (1-126): 7.6e-54: 166: 98.41
+	Hs
		707635 CHD4_HUMAN (48-1562): 0: 967: 25.57		H2B1B_HUMAN (1-126): 1.07e-53: 166: 95.24
+	Hs
		918368 CHD4_HUMAN (48-1562): 0: 967: 25.57		H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62
+	Hs
		886109 CHD4_HUMAN (48-1562): 0: 967: 25.57		H2B1D_HUMAN (1-126): 1.97e-53: 165: 96.83
+	Hs
		1059827 CHD4_HUMAN (48-1562): 0: 967: 25.57		H2B1L_HUMAN (1-126): 1.71e-52: 163: 96.03
+	Hs
		1059782 CHD4_HUMAN (48-1562): 0: 967: 25.57		H2B1A_HUMAN (1-126): 2.57e-46: 147: 81.89
+	Hs
		241591 CHD5_HUMAN (148-1580): 0: 942: 24.97		H2B1K_HUMAN (1-126): 7.6e-54: 166: 98.41
+	Hs
		918541 CHD5_HUMAN (148-1580): 0: 942: 24.97		H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62
+	Hs
		1087449 CHD7_HUMAN (7-1703): 0: 937: 21.90		H2B2E_HUMAN (1-126): 3.9e-54: 167: 96.83
+	Hs
		707773 CHD7_HUMAN (7-1703): 0: 937: 21.90		H2B1B_HUMAN (1-126): 1.07e-53: 166: 95.24
+	Hs
		918744 CHD7_HUMAN (7-1703): 0: 937: 21.90		H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62
+	Hs
		707755 CHD8_HUMAN (35-1648): 0: 926: 23.19		H2B1B_HUMAN (1-126): 1.07e-53: 166: 95.24
+	Hs
		918705 CHD8_HUMAN (35-1648): 0: 926: 23.19		H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62