Protein: CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4 (EC 3.1.13.4) (Carbon catabolite repressor protein 4) (Cytoplasmic deadenylase) (Glucose-repressible alcohol dehydrogenase transcriptional effector)

Gene: CCR4
Organism: Saccharomyces cerevisiae S288C
Interactions: 108
UniProt ID: P31384

Gene Ontology (top 5):
GO:0000076 - DNA replication checkpoint signaling
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

645889

DBF2
Cell cycle protein kinase DBF2

3

7

Small-scale

0.884

High

726212

POP2
Poly(A) ribonuclease POP2

21

13

Small-scale

0.769

High

678934

NOT1
General negative regulator of transcription subunit 1

16

9

Small-scale

0.764

High

726235

CAF40
Protein CAF40

11

5

Small-scale

0.759

High

726204

NOT4
General negative regulator of transcription subunit 4

12

3

Small-scale

0.757

High

438129

NOT2
General negative regulator of transcription subunit 2

6

10

Small-scale

0.730

High

726255

NOT5
General negative regulator of transcription subunit 5

5

6

Small-scale

0.721

High

726233

CF130
Protein CAF130

6

0

Small-scale

0.706

High

726199

PP12
Serine/threonine-protein phosphatase PP1-2

1

12

High-throughput

0.691

High

726195

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

19

High-throughput

0.665

High

726214

SSN3
Meiotic mRNA stability protein kinase SSN3

1

2

Small-scale

0.665

High

438267

NOT3
General negative regulator of transcription subunit 3

3

6

Small-scale

0.658

High

726220

NACB2
Nascent polypeptide-associated complex subunit beta-2

3

3

Small-scale

0.650

High

726240

PRS8
26S proteasome regulatory subunit 8 homolog

2

1

Small-scale

0.621

High

726247

PUF3
mRNA-binding protein PUF3

2

4

Small-scale

0.611

High

403402

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

7

Small-scale

0.585

High

592079

VATB
V-type proton ATPase subunit B

2

3

High-throughput

0.584

High

675792

MAS5
Mitochondrial protein import protein MAS5

2

6

High-throughput

0.584

High

726213

MPT5
Suppressor protein MPT5

2

4

Small-scale

0.584

High

726253

HSP42
Heat shock protein 42

2

2

High-throughput

0.584

High

726239

ACT
Actin

1

5

High-throughput

0.578

High

523305

HSP71
Heat shock protein SSA1

2

7

High-throughput

0.571

High

726200

SMY2
Protein SMY2

2

0

Small-scale

0.559

High

544103

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.552

High

726218

SSB2
Ribosome-associated molecular chaperone SSB2

2

7

High-throughput

0.552

High

726203

GCN1
eIF-2-alpha kinase activator GCN1

2

3

High-throughput

0.549

High

435835

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.546

High

585599

STI1
Heat shock protein STI1

1

10

High-throughput

0.536

High

726234

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.536

High

726244

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.536

High

726229

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

2

1

Small-scale

0.535

High

670438

SIS1
Protein SIS1

2

3

High-throughput

0.521

High

726238

LSM3
LSM complex subunit LSM3

1

0

High-throughput

0.518

High

625946

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.513

High

726197

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.513

High

726232

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.513

High

726207

CAF4
CCR4-associated factor 4

1

8

Small-scale

0.508

High

726241

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

3

Small-scale

0.508

High

509440

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

8

High-throughput

0.501

High

585689

UBC4
Ubiquitin-conjugating enzyme E2 4

1

3

Small-scale

0.501

High

386615

TBB
Tubulin beta chain

1

2

High-throughput

0.500

High

453469

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.500

High

486077

TBA1
Tubulin alpha-1 chain

1

3

High-throughput

0.500

High

531268

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.500

High

590565

HSP26
Heat shock protein 26

1

2

High-throughput

0.500

High

671591

SCJ1
DnaJ-related protein SCJ1

1

3

High-throughput

0.500

High

726248

SGT1
Protein SGT1

1

14

High-throughput

0.494

High

726250

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.489

High

726217

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.486

High

726226

CAF16
CCR4-associated factor 16

1

0

Small-scale

0.486

High

721584

RENT1
ATP-dependent helicase NAM7

1

3

Small-scale

0.481

High

408299

GAL1
Galactokinase

1

0

High-throughput

0.479

High

401922

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.479

High

534229

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

2

Small-scale

0.479

High

594246

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

661147

SPT6
Transcription elongation factor SPT6

1

2

Small-scale

0.479

High

672094

PUF4
Pumilio homology domain family member 4

1

4

Small-scale

0.479

High

721350

MCM4
DNA replication licensing factor MCM4

1

2

Small-scale

0.479

High

726201

PRS6A
26S proteasome regulatory subunit 6A

1

1

Small-scale

0.479

High

726206

DEF1
RNA polymerase II degradation factor 1

1

3

High-throughput

0.479

High

726208

GBLP
Small ribosomal subunit protein RACK1

1

7

Small-scale

0.479

High

726209

ANM1
Protein arginine N-methyltransferase 1

1

5

Small-scale

0.479

High

726221

TM108
Protein TMA108

1

5

High-throughput

0.479

High

726237

APJ1
J domain-containing protein APJ1

1

5

High-throughput

0.479

High

726249

TMA46
Translation machinery-associated protein 46

1

2

High-throughput

0.479

High

726254

DBP10
ATP-dependent RNA helicase DBP10

1

5

High-throughput

0.479

High

726256

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

6

Small-scale

0.479

High

726227

MDV1
Mitochondrial division protein 1

1

8

High-throughput

0.464

High

558626

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

605876

HPR1
THO complex subunit HPR1

1

0

Small-scale

0.458

High

688976

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.458

High

726196

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

Small-scale

0.458

High

726210

PAF1
RNA polymerase II-associated protein 1

1

0

Small-scale

0.458

High

726225

T2FB
Transcription initiation factor IIF subunit beta

1

0

Small-scale

0.458

High

726236

CA120
CCR4-NOT transcriptional complex subunit CAF120

1

0

Small-scale

0.458

High

726243

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

726246

CDC73
Cell division control protein 73

1

0

Small-scale

0.458

High

726252

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

366964

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.457

High

452850

ATPA
ATP synthase subunit alpha, mitochondrial

1

3

High-throughput

0.457

High

554892

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.457

High

626637

HSP60
Heat shock protein 60, mitochondrial

1

2

High-throughput

0.457

High

392381

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.445

High

427174

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

526134

HSP72
Heat shock protein SSA2

1

7

High-throughput

0.445

High

531649

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.445

High

726198

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

726202

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

726205

MDJ1
DnaJ homolog 1, mitochondrial

1

5

High-throughput

0.445

High

726219

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.445

High

726224

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.445

High

706438

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

726215

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.426

High

726230

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.426

High

726222

DJP1
DnaJ-like protein 1

1

5

High-throughput

0.407

High

726216

TCPZ
T-complex protein 1 subunit zeta

2

0

High-throughput

0.313

High

726211

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.299

High

673083

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.279

Low

726242

YM46
Uncharacterized protein YMR181C

1

0

High-throughput

0.265

Low

550035

RAP1
DNA-binding protein RAP1

1

0

Small-scale

0.261

Low

405050

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

548819

TAF13
Transcription initiation factor TFIID subunit 13

1

0

Small-scale

0.251

Low

726223

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

726228

YJY1
Uncharacterized protein YJR011C

1

0

High-throughput

0.249

Low

726231

TAF4
Transcription initiation factor TFIID subunit 4

1

0

High-throughput

0.249

Low

726245

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

726251

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025