Interactor 1: IRS4 (O14654)
Insulin receptor substrate 4 (IRS-4) (160 kDa phosphotyrosine protein) (py160) (Phosphoprotein of 160 kDa) (pp160)
Gene: IRS4

Interactor 2: MERL (P35240)
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin)
Gene: NF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 26549023
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FERM_M~IRS, FERM_N~IRS
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1257
Hs

1 595
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024