Interactor 1: APAF (O14727)
Apoptotic protease-activating factor 1 (APAF-1)
Gene: APAF1
Interactor 2: CASP4 (P49662)
Caspase-4 (CASP-4) (EC 3.4.22.57) (ICE and Ced-3 homolog 2) (ICH-2) (ICE(rel)-II) (Mih1) (Protease TX) [Cleaved into: Caspase-4 subunit p10; Caspase-4 subunit p20]
Gene: CASP4
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9539746 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD, CARD~NB-ARC |
| Common GO terms | GO:0005576 - extracellular region GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0032991 - protein-containing complex GO:0070059 - intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and 1 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Rn |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
