Protein: SDE2
Splicing regulator sde2 (Silencing defective protein 2) (Telomere maintenance protein SDE2)

Gene: SDE2
Organism: Schizosaccharomyces pombe 972h-
Interactions: 79
UniProt ID: O14113

Gene Ontology (top 5):
GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0005829 - cytosol
GO:0045292 - mRNA cis splicing, via spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

152506

PRP19
Pre-mRNA-processing factor 19

3

0

Small-scale

0.628

High

152831

CWF14
Pre-mRNA-splicing factor cwf14

3

0

Small-scale

0.613

High

152846

CWC2
Pre-mRNA-splicing factor cwf2

3

0

Small-scale

0.613

High

152862

YK96
Uncharacterized protein C20H4.06c

3

0

Small-scale

0.613

High

152814

CWC21
Pre-mRNA-splicing factor cwf21

2

0

Small-scale

0.585

High

152828

ISY1
Pre-mRNA-splicing factor cwf12

2

0

Small-scale

0.585

High

152822

PRP17
Pre-mRNA-processing factor 17

2

1

Small-scale

0.584

High

152852

CWF19
Pre-mRNA-splicing factor cwf19

2

1

Small-scale

0.584

High

152853

RSMB
Small nuclear ribonucleoprotein-associated protein B

2

2

Small-scale

0.584

High

152861

YK99
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase C20H4.09

2

2

Small-scale

0.584

High

152874

BRR2
Pre-mRNA-splicing factor brr2

2

2

Small-scale

0.584

High

152824

SYF2
Pre-mRNA-splicing factor syf2

2

0

Small-scale

0.559

High

152826

SLT11
Pre-mRNA-splicing factor cwf5

2

0

Small-scale

0.559

High

152835

SN114
Pre-mRNA-splicing factor cwf10

2

0

Small-scale

0.559

High

152836

CWC26
Pre-mRNA-splicing factor cwf26

2

0

Small-scale

0.559

High

152838

CWF17
Pre-mRNA-splicing factor cwf17

2

0

Small-scale

0.559

High

152844

CWC15
Pre-mRNA-splicing factor cwf15

2

0

Small-scale

0.559

High

152845

SRP2
Pre-mRNA-splicing factor srp2

2

0

Small-scale

0.559

High

152855

SRP1
Pre-mRNA-splicing factor srp1

2

0

Small-scale

0.559

High

152870

SPF27
Pre-mRNA-splicing factor cwf7

2

0

Small-scale

0.559

High

152871

RU2A
U2 small nuclear ribonucleoprotein A'

2

0

Small-scale

0.559

High

152878

CWF18
Pre-mRNA-splicing factor cwf18

2

0

Small-scale

0.559

High

152882

CWC25
Pre-mRNA-splicing factor cwf25

2

0

Small-scale

0.559

High

152843

CEF1
Pre-mRNA-splicing factor cdc5

2

0

Small-scale

0.547

High

152795

SAP49
Spliceosome-associated protein 49

1

0

Small-scale

0.513

High

152817

CATIN
Splicing factor cactin

1

0

Small-scale

0.513

High

151427

YE02
Uncharacterized helicase C17H9.02

1

1

High-throughput

0.479

High

152818

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22

1

1

Small-scale

0.479

High

152819

SMD1
Small nuclear ribonucleoprotein Sm D1

1

1

Small-scale

0.479

High

152820

YFH9
Uncharacterized RNA-binding protein C23A1.09

1

1

Small-scale

0.479

High

152825

RUXF
Small nuclear ribonucleoprotein F

1

1

Small-scale

0.479

High

152829

LSM7
LSM complex subunit lsm7

1

2

Small-scale

0.479

High

152832

RUXG
Small nuclear ribonucleoprotein G

1

3

Small-scale

0.479

High

152833

RU1A
U1 small nuclear ribonucleoprotein usp102

1

1

Small-scale

0.479

High

152834

PRP39
Pre-mRNA-processing factor 39

1

6

Small-scale

0.479

High

152847

CLF1
Pre-mRNA-splicing factor cwf4

1

5

Small-scale

0.479

High

152856

MU161
CWF19-like protein mug161

1

1

Small-scale

0.479

High

152857

CDC28
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein cdc28

1

1

Small-scale

0.479

High

152858

PRP1
Pre-mRNA-splicing factor prp1

1

3

Small-scale

0.479

High

152859

RU2B
Probable U2 small nuclear ribonucleoprotein B''

1

1

Small-scale

0.479

High

152868

SYF1
Pre-mRNA-splicing factor cwf3

1

4

Small-scale

0.479

High

152872

SART3
U4/U6 snRNA-associated-splicing factor prp24

1

1

Small-scale

0.479

High

152879

SMD3
Small nuclear ribonucleoprotein Sm D3

1

2

Small-scale

0.479

High

150421

PRP46
Pre-mRNA-splicing factor prp5

1

0

Small-scale

0.458

High

151184

YF28
Uncharacterized protein C17A2.08c

1

0

High-throughput

0.458

High

151777

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

0

Small-scale

0.458

High

151927

SA114
Pre-mRNA-splicing factor sap114

1

0

Small-scale

0.458

High

152497

NSRP1
Nuclear speckle splicing regulatory protein 1 homolog

1

0

Small-scale

0.458

High

152633

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

Small-scale

0.458

High

152813

SEM1
26S proteasome complex subunit rpn15

1

0

High-throughput

0.458

High

152815

PRP40
Pre-mRNA-processing protein prp40

1

0

Small-scale

0.458

High

152816

SPP42
Pre-mRNA-splicing factor spp42

1

0

Small-scale

0.458

High

152821

PRP31
Pre-mRNA-processing factor 31

1

0

Small-scale

0.458

High

152823

SAP61
Pre-mRNA-splicing factor sap61

1

0

Small-scale

0.458

High

152827

CWC16
Protein saf4

1

0

Small-scale

0.458

High

152830

BBP
Branchpoint-bridging protein

1

0

Small-scale

0.458

High

152837

CWF11
Pre-mRNA-splicing factor cwf11

1

0

Small-scale

0.458

High

152839

US109
U1 snRNP-associated protein usp109

1

0

Small-scale

0.458

High

152840

HUB1
Ubiquitin-like modifier hub1

1

0

Small-scale

0.458

High

152841

DSK1
Protein kinase dsk1

1

0

Small-scale

0.458

High

152842

U2AF2
Splicing factor U2AF 59 kDa subunit

1

0

Small-scale

0.458

High

152848

GAR1
H/ACA ribonucleoprotein complex subunit gar1

1

0

Small-scale

0.458

High

152849

U2AF1
Splicing factor U2AF 23 kDa subunit

1

0

Small-scale

0.458

High

152850

US108
U1 snRNP-associated protein usp108

1

0

Small-scale

0.458

High

152851

PRP45
Pre-mRNA-processing protein 45

1

0

Small-scale

0.458

High

152854

SF3B1
U2 snRNP component prp10

1

0

Small-scale

0.458

High

152860

US107
U1 snRNP-associated protein usp107

1

0

Small-scale

0.458

High

152863

RU1C
U1 small nuclear ribonucleoprotein C

1

0

Small-scale

0.458

High

152864

PRP11
Pre-mRNA-processing ATP-dependent RNA helicase prp11

1

0

Small-scale

0.458

High

152865

NHP2
H/ACA ribonucleoprotein complex subunit nhp2

1

0

Small-scale

0.458

High

152866

SAP62
Pre-mRNA-splicing factor sap62

1

0

Small-scale

0.458

High

152869

LUC7
U1 snRNP-associated protein usp106

1

0

Small-scale

0.458

High

152873

RUXE
Small nuclear ribonucleoprotein E

1

0

Small-scale

0.458

High

152875

INI1
Pre-mRNA-splicing factor ini1

1

0

Small-scale

0.458

High

152876

YKR3
G-patch domain-containing protein C1486.03

1

0

High-throughput

0.458

High

152877

RSE1
Pre-mRNA-splicing factor prp12

1

0

Small-scale

0.458

High

152880

SA145
Pre-mRNA-splicing factor sap145

1

0

Small-scale

0.458

High

152881

SLU7
Pre-mRNA-splicing factor slu7

1

0

Small-scale

0.458

High

152867

NOP10
H/ACA ribonucleoprotein complex subunit nop10

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025