HitPredict

Interactor 1: APAF (O14727)
Apoptotic protease-activating factor 1 (APAF-1)
Gene: APAF1

Interactor 2: DEFI8 (Q6ZN54)
Differentially expressed in FDCP 8 homolog (DEF-8)
Gene: DEF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1248 Hs			1 512
+	Hs
		566468 TEP1_HUMAN (844-1247): 2.96e-58: 224: 16.74		KPCA_HUMAN (151-250): 2.8e-20: 96.3: 16.83
+	Hs
		929405 RACK1_HUMAN (964-1207): 2.09e-10: 65.5: 25.29		KPCE_HUMAN (151-250): 8.06e-23: 104: 17.43
+	Hs
		408594 RACK1_HUMAN (964-1207): 2.09e-10: 65.5: 25.29		KPCB_HUMAN (151-269): 6.29e-21: 98.3: 15.00
+	Mm
		932614 RACK1_MOUSE (964-1207): 2.09e-10: 65.5: 25.29		KPCB_MOUSE (151-269): 5.86e-21: 98.3: 15.00
+	Hs
		566350 RACK1_HUMAN (964-1207): 2.09e-10: 65.5: 25.29		KPCA_HUMAN (151-250): 2.8e-20: 96.3: 16.83