Interactor 1: NHRF1 (O14745)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
Gene: NHERF1

Interactor 2: PIN1 (Q13526)
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase Pin1) (PPIase Pin1) (Rotamase Pin1)
Gene: PIN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 11533036
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0008013 - beta-catenin binding
GO:0070373 - negative regulation of ERK1 and ERK2 cascade
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 358
Hs

1 163
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024