Interactor 1: CHK1 (O14757)
Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)
Gene: CHEK1
Interactor 2: CLSPN (Q9HAW4)
Claspin (hClaspin)
Gene: CLSPN
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.761 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23598722, 35048968, 21680713, 16963448, 16123041, 12766152, 22732499, 17276990, 15707391, 26082189, 16880517, 23109433 |
| Identification Methods | affinity chromatography technology, pull down, enzymatic study, protein kinase assay, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000077 - DNA damage checkpoint signaling GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0007095 - mitotic G2 DNA damage checkpoint signaling |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
