Protein: ZFY16
Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein)

Gene: ZFY16, ZFYVE16
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q7Z3T8

Gene Ontology (top 5):
GO:0005545 - 1-phosphatidylinositol binding
GO:0005547 - phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0006622 - protein targeting to lysosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

241175

TOM1
Target of Myb1 membrane trafficking protein

3

17

Small-scale

0.885

High

1067441

EEA1
Early endosome antigen 1

2

14

Small-scale

0.754

High

1189523

ANFY1
Rabankyrin-5

2

7

Small-scale

0.754

High

905987

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

5

14

High-throughput

0.722

High

737894

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

4

14

High-throughput

0.699

High

1189516

PTN23
Tyrosine-protein phosphatase non-receptor type 23

3

7

Small-scale

0.662

High

160062

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

19

Small-scale

0.618

High

277083

STAM2
Signal transducing adapter molecule 2

1

20

Small-scale

0.618

High

313553

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

14

Small-scale

0.618

High

475975

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

10

Small-scale

0.595

High

338627

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.584

High

591904

RAB4A
Ras-related protein Rab-4A

2

13

High-throughput

0.584

High

845568

RAB9A
Ras-related protein Rab-9A

2

20

High-throughput

0.584

High

1189518

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

1189519

ELP3
Elongator complex protein 3

1

1

High-throughput

0.536

High

364329

TFR1
Transferrin receptor protein 1

1

2

High-throughput

0.515

High

1045445

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

11

High-throughput

0.515

High

1189530

RNF11
RING finger protein 11

1

3

High-throughput

0.508

High

395044

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

178623

STX7
Syntaxin-7

1

8

High-throughput

0.479

High

212899

STX6
Syntaxin-6

1

6

High-throughput

0.479

High

294976

RECQ4
ATP-dependent DNA helicase Q4

1

6

High-throughput

0.479

High

350295

RASK
GTPase KRas

1

14

High-throughput

0.479

High

386997

P53
Cellular tumor antigen p53

1

3

Small-scale

0.479

High

451482

CLCA
Clathrin light chain A

1

3

High-throughput

0.479

High

452449

PGFRB
Platelet-derived growth factor receptor beta

1

20

High-throughput

0.479

High

456600

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

1

Small-scale

0.479

High

507089

LAMP1
Lysosome-associated membrane glycoprotein 1

1

13

High-throughput

0.479

High

508079

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

514031

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

2

Small-scale

0.479

High

527568

LAMP2
Lysosome-associated membrane glycoprotein 2

1

13

High-throughput

0.479

High

545466

RAC2
Ras-related C3 botulinum toxin substrate 2

1

18

High-throughput

0.479

High

564590

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

567136

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

575770

VINC
Vinculin

1

3

High-throughput

0.479

High

592340

RAB5A
Ras-related protein Rab-5A

1

19

High-throughput

0.479

High

651554

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

665621

EPHB2
Ephrin type-B receptor 2

1

20

High-throughput

0.479

High

670973

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

4

Small-scale

0.479

High

723991

CBS
Cystathionine beta-synthase

1

1

Small-scale

0.479

High

738365

BMR1A
Bone morphogenetic protein receptor type-1A

1

2

Small-scale

0.479

High

738464

ACV1B
Activin receptor type-1B

1

2

Small-scale

0.479

High

738554

TGFR1
TGF-beta receptor type-1

1

2

Small-scale

0.479

High

779652

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

844588

RAB5C
Ras-related protein Rab-5C

1

19

High-throughput

0.479

High

845029

RAB7A
Ras-related protein Rab-7a

1

20

High-throughput

0.479

High

872668

EPHA4
Ephrin type-A receptor 4

1

19

High-throughput

0.479

High

892453

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

906513

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

14

Small-scale

0.479

High

908745

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

914169

RB11A
Ras-related protein Rab-11A

1

6

High-throughput

0.479

High

915790

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

924051

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

5

Small-scale

0.479

High

925390

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

951110

RHOG
Rho-related GTP-binding protein RhoG

1

18

High-throughput

0.479

High

965732

IFM3
Interferon-induced transmembrane protein 3

1

11

High-throughput

0.479

High

974894

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

1035486

SMAD4
Mothers against decapentaplegic homolog 4

1

12

Small-scale

0.479

High

1038489

HDAC1
Histone deacetylase 1

1

3

High-throughput

0.479

High

1132657

FKB15
FK506-binding protein 15

1

10

Small-scale

0.479

High

1148116

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.479

High

1151934

LTOR1
Ragulator complex protein LAMTOR1

1

8

High-throughput

0.479

High

1158618

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

1

Small-scale

0.479

High

1183435

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1188269

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.479

High

1188489

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.479

High

1189509

VP37A
Vacuolar protein sorting-associated protein 37A

1

2

Small-scale

0.479

High

1189511

PDC6I
Programmed cell death 6-interacting protein

1

18

Small-scale

0.479

High

1189512

PF21A
PHD finger protein 21A

1

3

High-throughput

0.479

High

1189513

TS101
Tumor susceptibility gene 101 protein

1

4

Small-scale

0.479

High

1189515

TOLIP
Toll-interacting protein

1

2

High-throughput

0.479

High

1189524

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

1189528

MYO6
Unconventional myosin-VI

1

9

High-throughput

0.479

High

1189529

LAMP3
Lysosome-associated membrane glycoprotein 3

1

13

High-throughput

0.479

High

428687

TRY1
Serine protease 1

1

0

Small-scale

0.458

High

1146112

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.458

High

1189507

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1189522

UBAP1
Ubiquitin-associated protein 1

1

0

Small-scale

0.458

High

1189526

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

Small-scale

0.458

High

169508

BET1
BET1 homolog

1

6

High-throughput

0.437

High

205593

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.437

High

232277

KDM1A
Lysine-specific histone demethylase 1A

1

2

High-throughput

0.437

High

525974

IFM1
Interferon-induced transmembrane protein 1

1

11

High-throughput

0.437

High

553052

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

557174

PGFRA
Platelet-derived growth factor receptor alpha

1

20

High-throughput

0.437

High

601538

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.437

High

608024

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.437

High

720790

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

872453

EPHA5
Ephrin type-A receptor 5

1

20

High-throughput

0.437

High

884525

RAB25
Ras-related protein Rab-25

1

7

High-throughput

0.437

High

1072532

EPHA7
Ephrin type-A receptor 7

1

16

High-throughput

0.437

High

1168379

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.437

High

1170581

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1189508

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.437

High

1189510

SNX29
Sorting nexin-29

1

8

Small-scale

0.437

High

1189514

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.437

High

1189517

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.437

High

1189520

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.437

High

1189521

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

4

High-throughput

0.437

High

1189525

PEF1
Peflin

1

3

Small-scale

0.437

High

1189527

RCOR1
REST corepressor 1

1

3

High-throughput

0.437

High

522029

CADH1
Cadherin-1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024