HitPredict

Interactor 1: TR10B (O14763)
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)
Gene: TNFRSF10B

Interactor 2: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 822
+	Hs
		121442 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		FGFR3_HUMAN (6-821): 0: 730: 61.22
+	Hs
		507889 TNR3_HUMAN (46-339): 3.8e-35: 137: 16.57		FGFR1_HUMAN (1-822): 0: 861: 100.00
+	Hs
		121441 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		FGFR4_HUMAN (29-808): 0: 664: 55.60
+	Hs
		507951 PGBM_HUMAN (32-267): 4.36e-17: 86.2: 15.53		FGFR1_HUMAN (1-822): 0: 861: 100.00
+	Hs
		601615 EDAR_HUMAN (42-327): 3.58e-34: 134: 12.75		FGFR2_HUMAN (1-821): 0: 803: 71.21
+	Hs
		609252 PGBM_HUMAN (32-267): 4.36e-17: 86.2: 15.53		FGFR3_HUMAN (6-821): 0: 730: 61.22
+	Hs
		608195 EDAR_HUMAN (42-327): 3.58e-34: 134: 12.75		FGFR4_HUMAN (29-808): 0: 664: 55.60
+	Hs
		665365 EDAR_HUMAN (42-327): 3.58e-34: 134: 12.75		EPHA2_HUMAN (3-819): 0: 583: 18.68
+	Hs
		313616 TNF6B_HUMAN (61-222): 9.76e-28: 113: 20.47		EPHA8_HUMAN (3-819): 0: 603: 19.35
+	Hs
		872593 EDAR_HUMAN (42-327): 3.58e-34: 134: 12.75		EPHB4_HUMAN (3-777): 2.12e-180: 546: 17.74
+	Hs
		436626 TNR16_HUMAN (53-393): 6.19e-51: 179: 16.30		NTRK2_HUMAN (102-762): 5.62e-163: 495: 22.70
+	Rn
		421812 TNR16_RAT (53-393): 2.11e-50: 177: 16.30		NTRK2_RAT (111-762): 4.27e-163: 496: 23.89
+	Rn
		421810 TNR16_RAT (53-393): 2.11e-50: 177: 16.30		NTRK3_RAT (163-762): 8.71e-158: 483: 24.28
+	Rn
		421808 TNR16_RAT (53-393): 2.11e-50: 177: 16.30		NTRK1_RAT (160-769): 6.2e-144: 445: 27.76
+	Hs
		384118 TNR16_HUMAN (53-393): 6.19e-51: 179: 16.30		NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96
+	Mm
		626887 TNR1B_MOUSE (38-303): 2.67e-33: 132: 18.64		NTRK1_MOUSE (160-769): 5.75e-143: 442: 27.97
+	Hs
		729678 TNR25_HUMAN (58-424): 4.73e-60: 203: 19.24		VGFR2_HUMAN (43-343): 3.9e-15: 82.1: 16.26
+	Hs
		572620 PGBM_HUMAN (32-267): 4.36e-17: 86.2: 15.53		VGFR1_HUMAN (48-362): 8.54e-23: 107: 18.73
+	Hs
		729641 PGBM_HUMAN (32-267): 4.36e-17: 86.2: 15.53		VGFR2_HUMAN (43-343): 3.9e-15: 82.1: 16.26