HitPredict

Interactor 1: TR10B (O14763)
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)
Gene: TNFRSF10B

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31478661, 31871319
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 440 Hs			1 191
+	Hs
		154305 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		154414 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		154338 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		154343 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		154335 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		154300 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		154295 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		154332 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		154380 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82
+	Hs
		121438 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		121534 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		121470 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		121466 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		121472 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		121467 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		121436 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		121431 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		121464 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		121501 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82
+	Hs
		436154 TNR1A_HUMAN (46-422): 1.95e-65: 218: 19.72		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41