HitPredict

Interactor 1: TR10B (O14763)
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)
Gene: TNFRSF10B

Interactor 2: SLAF1 (Q13291)
Signaling lymphocytic activation molecule (CDw150) (IPO-3) (SLAM family member 1) (CD antigen CD150)
Gene: SLAMF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0038023 - signaling receptor activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 335
+	Hs
		154297 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		68218 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		HECA2_HUMAN (1-329): 2.97e-24: 104: 17.39
+	Hs
		1030730 FRAS1_HUMAN (8-330): 8.46e-11: 66.6: 12.47		SLAF1_HUMAN (1-335): 3.45e-80: 249: 100.00
+	Hs
		1030715 LAMA3_HUMAN (81-201): 7.52e-10: 63.5: 18.37		SLAF1_HUMAN (1-335): 3.45e-80: 249: 100.00
+	Hs
		507889 TNR3_HUMAN (46-339): 3.8e-35: 137: 16.57		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		507951 PGBM_HUMAN (32-267): 4.36e-17: 86.2: 15.53		FGFR1_HUMAN (20-333): 4.68e-46: 168: 9.12
+	Hs
		601615 EDAR_HUMAN (42-327): 3.58e-34: 134: 12.75		FGFR2_HUMAN (24-327): 1.1e-23: 103: 10.29
+	Mm
		632459 TNR6_MOUSE (61-184): 1.08e-28: 117: 24.24		CEAM1_MOUSE (73-235): 3.84e-24: 104: 18.90
+	Hs
		685264 FRAS1_HUMAN (8-330): 8.46e-11: 66.6: 12.47		CEAM8_HUMAN (45-251): 6.59e-22: 96.5: 16.51
+	Hs
		1204968 FRAS1_HUMAN (8-330): 8.46e-11: 66.6: 12.47		PSG8_HUMAN (13-241): 1.78e-20: 93.4: 15.09
+	Hs
		685247 LAMA3_HUMAN (81-201): 7.52e-10: 63.5: 18.37		CEAM8_HUMAN (45-251): 6.59e-22: 96.5: 16.51