HitPredict

Interactor 1: TR10B (O14763)
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)
Gene: TNFRSF10B

Interactor 2: MARH8 (Q5T0T0)
E3 ubiquitin-protein ligase MARCHF8 (EC 2.3.2.27) (Cellular modulator of immune recognition) (c-MIR) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII) (RING finger protein 178) (RING-type E3 ubiquitin transferase MARCHF8)
Gene: MARCHF8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	32614325, 36867660
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 291
+	Hs
		121494 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		MARH8_HUMAN (1-291): 1.77e-109: 320: 100.00
+	Hs
		154389 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		MARH1_HUMAN (5-291): 6.93e-84: 255: 64.46
+	Hs
		121513 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		MARH1_HUMAN (5-291): 6.93e-84: 255: 64.46
+	Hs
		154422 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		MARH2_HUMAN (48-257): 8.13e-49: 164: 25.82
+	Hs
		154381 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		MARH3_HUMAN (55-253): 1.93e-48: 163: 24.26
+	Hs
		632297 TNR6_HUMAN (52-184): 2.49e-31: 124: 25.53		MARH8_HUMAN (1-291): 1.77e-109: 320: 100.00