HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: NEK2 (P51955)
Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1)
Gene: NEK2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.664

The method score is based on:

Property Details
Experiments 12386167, 9295362, 21900206
Identification Methods pull down, two hybrid, enzymatic study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000278 - mitotic cell cycle
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005813 - centrosome
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 642
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024