HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 26638075, 34079125
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000132 - establishment of mitotic spindle orientation
GO:0000278 - mitotic cell cycle
GO:0000776 - kinetochore
GO:0005813 - centrosome
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 642
Hs

1 1278
+ Xl
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+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Rn
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+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024